Attention-Deficit/Hyperactivity Disorder

DuPaul, George J.; Pollack, Brittany; Pinho, Trevor

doi:10.1007/978-3-319-57196-6_20

Handbook of DSM-5 Disorders in Children and Adolescents 2017

DOI: 10.1007/978-3-319-57196-6_20

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Attention-Deficit/Hyperactivity Disorder

George J. DuPaul¹,

Brittany Pollack²,

Trevor Pinho³

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2024

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Cited by 1 publication

References 92 publications

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Exploring the impact of probiotics on adult ADHD management through a double-blind RCT

Levy Schwartz,

Magzal,

Yehuda

et al. 2024

Sci Rep

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Attention deficit hyperactivity disorder (ADHD) is a common neuropsychiatric condition often persisting into adulthood, characterized by inattention, impulsivity, and hyperactivity. Emerging research suggests a connection between ADHD and gut microbiota, highlighting probiotics as potential therapeutic agents. This study involved a double-blind, randomized controlled trial where college students with ADHD received either a multi-strain probiotic supplement or a placebo daily for three months. ADHD symptoms were evaluated using a computerized performance test (MOXO) and the MATAL questionnaire. Academic records provided performance data. Additionally, eating and sleeping habits, gastrointestinal symptoms, and anthropometrics were assessed through questionnaires before and after the intervention. Fingernail cortisol concentrations (FCC) measured the long-term activity of the hypothalamic–pituitary–adrenal axis. The findings indicated that the probiotic significantly decreased hyperactivity, improved gastrointestinal symptoms, and enhanced academic performance. A multivariate analysis identified age as a significant predictor, with younger participants experiencing greater overall benefits from the intervention. There was also a negative correlation between FCC and symptoms of attention and impulsivity. Furthermore, higher academic grades were associated with lower levels of hyperactivity and impulsivity. These results suggest a beneficial impact of probiotics on ADHD symptoms and lay the groundwork for further studies to evaluate the effects of various probiotic strains on clinical outcomes in ADHD. Supplementary Information The online version contains supplementary material available at 10.1038/s41598-024-73874-y.

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Exploring the impact of probiotics on adult ADHD management through a double-blind RCT

Levy Schwartz,

Magzal,

Yehuda

et al. 2024

Sci Rep

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

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Attention-Deficit/Hyperactivity Disorder

Cited by 1 publication

References 92 publications

Exploring the impact of probiotics on adult ADHD management through a double-blind RCT

Exploring the impact of probiotics on adult ADHD management through a double-blind RCT

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