Attenuation Coefficient Estimation of Normal Placentas

Fast linear least-squares method for ultrasound attenuation and backscatter estimation

“…Finally, an ultimate testing of the proposed methodology needs to be performed in-vivo. In this context, when a homogeneous ROI is of clinical interest [39], the proposed LLS method could be directly applied for the coefficient estimation. However, when the heterogeneity of the underlying tissue needs to be captured by building its attenuation and backscatter coefficient maps, a generalization of our method towards a heterogeneous, i.e.…”

“…To compare the DP method with our approach on the considered data sets, the implementation details for the DP method are as follows. First, while in the original paper, the authors considered a RPM based model (such as in equation ( 5)), here when working in the absence of a reference phantom, the model was adapted as done in our approach in equation (10). Second, the regularized cost function consisted of a data fidelity term and an 1 regularization term for each of the three parameters of interest, associated with their regularization weights.…”

“…In particular, attenuation estimation has been used to differentiate fatty liver from normal liver as well as to diagnose chronic liver diseases [5,6,7]. The attenuation measurements have also shown diagnostic value in areas including the trabecular and cortical bone [8,9], placentas [10], to name a few. An accurate estimate of the attenuation coefficient also allows to perform more accurate time gain compensation (TGC) in ultrasound images [11].…”

PredictUS: A Method to Extend the Resolution-Precision Trade-Off in Quantitative Ultrasound Image Reconstruction

“…According to this method, the RF data are acquired from both the tissue sample, s and a reference phantom, r with known properties using the same transducer and system settings. For a RF signal window centered at depth z from the transducer surface, the natural logarithm of the ratio of the power spectrum S from the sample to the reference phantom at frequency f ∈ (f 1 , f k ) can be written as [2,4]:…”

“…Extending beyond qualitative B-mode ultrasound imaging, QUS presents clinically significant parametric images, which are descriptive of underlying tissue microstructure. Recent studies show that QUS potentially provides effective, non-invasive, and system independent biomarkers for non-alcoholic fatty liver disease (NAFLD) detection and monitoring, cervical ripening detection, placenta characterization, and breast lesion characterization [1][2][3].…”