Attenuation correction in multipinhole-CZT gamma camera

Moncayo, Valeria; Galt, James R.

doi:10.1007/s12350-018-01498-7

Cited by 4 publications

(2 citation statements)

References 10 publications

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“…Some studies conclude that patients with body mass index (BMI) higher than forty should be scheduled for MPI on c-SPECT because of major artefacts [10]. Attenuation correction signi cantly decreases mean summed stress scores (SSS) and mean summed rest scores (SRS) in MPI with a CZT camera, improves the speci city of MPI with a CZT camera, and lowers the need for additional rest imaging in stress-rst MPI, decreasing the mean effective dose [11][12][13]. Understanding the attenuation pattern in MPI studies using CZT gamma cameras is crucial for physicians who do not use attenuation correction to prevent incorrect image interpretation [12].…”

Section: Introductionmentioning

confidence: 99%

“…Attenuation correction signi cantly decreases mean summed stress scores (SSS) and mean summed rest scores (SRS) in MPI with a CZT camera, improves the speci city of MPI with a CZT camera, and lowers the need for additional rest imaging in stress-rst MPI, decreasing the mean effective dose [11][12][13]. Understanding the attenuation pattern in MPI studies using CZT gamma cameras is crucial for physicians who do not use attenuation correction to prevent incorrect image interpretation [12]. Other MPI artefact sources are patient motion (PM) and cardiac respiratory motion (RM).…”

Section: Introductionmentioning

confidence: 99%

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Improving multi-pinhole CZT myocardial perfusion imaging specificity without changing sensibility by using adapted prefilter parameters

Vauchot,

Dubois,

Bourdon

2023

Preprint

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Background Meta-analysis show the diagnostic performance of cardiac dedicated multi-pinhole CZT (cadmium-zinc-telluride) myocardial perfusion imaging (MPI) with a sensibility around 0.9 and a specificity around 0.7. The aim of the present study is to explore a simple method to generate less artefact on MPI using single photon emission computed tomography (SPECT) and to enhance specificity without changing sensibility. Results From October 2018 to March 2019, 200 patients who underwent SPECT with [99mTc]Tc-tetrofosmin were prospectively recruited: 100 patients with ischemia or necrosis diagnosis (first arm), and 100 patients with myocardial reversible SPECT artefact (second arm). Each SPECT was explored using two image process based on a Butterworth prefilter: the original image processing (treatment A) with a cut-off frequency equals to 37% of the Nyquist frequency and order equals to 7, and a second image processing (treatment B) with a cut-off frequency equals to 25% of the Nyquist frequency and order equals to 5. For each patient, sum stress or rest score with and without septum (SSRS and SSRSws) were calculated with the two treatments. No significant statistical difference between SSRSa and SSRSb was identified for the first arm (P=0.54) and the relative difference ∆r was -0.5 ± 11.1 % (CI95 -2.6–1.8). We found a significant statistical difference between SSRSa and SSRSb for the second arm (p < 0.0001). Conclusion In conclusion, using a prefilter cut-off frequency equal to 25% of the Nyquist frequency before iterative reconstruction generates less artefact and improves myocardial SPECT specificity without affecting sensibility compared with the original treatment.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Improving multi-pinhole CZT myocardial perfusion imaging specificity without changing sensibility by using adapted prefilter parameters

Vauchot,

Dubois,

Bourdon

2023

Preprint

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Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2019: Single-photon emission computed tomography

Hage

AlJaroudi

2020

Journal of Nuclear Cardiology

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Improving multi-pinhole CZT myocardial perfusion imaging specificity without changing sensibility by using adapted filter parameters

Vauchot,

Dubois,

Bourdon

2024

EJNMMI Res

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Background Meta-analysis show the diagnostic performance of cardiac dedicated multi-pinhole cadmium-zinc-telluride myocardial perfusion imaging (MPI) with a sensibility around 0.9 and a specificity around 0.7. The aim of the present study is to explore a simple method to generate less artefact on MPI using single photon emission computed tomography (SPECT) and to enhance specificity without changing sensibility. Results From October 2018 to March 2019, 200 patients who underwent SPECT with [99mTc]Tc-tetrofosmin were prospectively recruited: 100 patients with ischemia or necrosis diagnosis (first arm), and 100 patients with myocardial reversible SPECT artefact (second arm). Each SPECT was explored using two image process based on a Butterworth prefilter and post-filter: the original image processing (reconstruction A) with a cut-off frequency equals to 37% of the Nyquist frequency and order equals to 7, and a second image processing (reconstruction B) with a cut-off frequency equals to 25% of the Nyquist frequency and order equals to 5. For each patient, sum stress or rest score with and without septum (SSRS and SSRSws) were calculated with the two reconstructions. No significant statistical difference between SSRSa and SSRSb was identified for the first arm (P = 0.54) and the relative difference ∆r was − 0.5 ± 11.1% (95% CI − 2.7 to 1.7). We found a significant statistical difference between SSRSa and SSRSb for the second arm (p < 0.0001) and the relative difference ∆r was 69.7 ± 16.2% (95% CI 66.6–72.9). Conclusion In conclusion, using a Butterworth prefilter and post-filter cut-off frequency equal to 25% of the Nyquist frequency before iterative reconstruction generates less artefact and improves myocardial SPECT specificity without affecting sensibility compared with the original reconstruction.

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Attenuation correction in multipinhole-CZT gamma camera

Cited by 4 publications

References 10 publications

Improving multi-pinhole CZT myocardial perfusion imaging specificity without changing sensibility by using adapted prefilter parameters

Improving multi-pinhole CZT myocardial perfusion imaging specificity without changing sensibility by using adapted prefilter parameters

Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2019: Single-photon emission computed tomography

Improving multi-pinhole CZT myocardial perfusion imaging specificity without changing sensibility by using adapted filter parameters

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