Attenuation of the Preoperative Stress Response with Midazolam

Kain, Zeev N.; Sevarino, Ferne B.; Pincus, Sharon; Alexander, Gerianne M.; Wang, Shu Ming; Ayoub, Chakib M.; Kosarussavadi, Boonsri

doi:10.1097/00000542-200007000-00024

Cited by 116 publications

(72 citation statements)

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“…혈장 ACTH는 코티졸에 비 해 먼저 분비되므로 스트레스에 대한 급성 변화를 잘 반영할 수 있다 [7]. 수술에 대한 불안과 스트레스 반응이 장기간 지속이 되면 수술 후에 통증에 대한 불안과 같은 심리적 합병증이 발생 하고 입원기간과 회복이 지연될 수 있다 [14]. 따라서 이런 간호 문제를 예방하기 위해 수술 중에 대상자들의 불안 감소와 진정 상태를 지속으로 유지시키고 스트레스 반응을 감소시킬 수 있 는 중재방법이 필요하다고 생각한다.…”

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The Effects of Music Therapy on Anxiety, Sedation, and Stress Responses of Patients Undergoing Surgery with Spinal Anesthesia

Jeong¹,

Kang

2016

Korean J Adult Nurs

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Purpose: This study was conducted to examine the effects of music therapy on anxiety, sedation, and stress responses of patients during surgery with spinal anesthesia. Methods: A quasi-experimental design with a non-equivalent control group pre-post test was used. There were 55 adults over 19 years of age scheduled for a lower leg surgery with spinal anesthesia: 27 in the treatment group and 28 in the comparison group. Each subject in the treatment group identified their music preference which was used during the period of surgery which usually lasted, 61 minutes. Data were analyzed using chi-square, Fisher's exact test, independent t-test and repeated measured ANOVA. Results: There were significant reported differences in levels of anxiety, sedation, and stress responses which were measured by plasma cortisol levels, heart rate, and respiratory rate. The findings of all the variables were effectively decreased among those in the treatment group than the comparison group. Conclusion: The preference based music therapy may be useful as a non-pharmacological intervention.

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The Effects of Music Therapy on Anxiety, Sedation, and Stress Responses of Patients Undergoing Surgery with Spinal Anesthesia

Jeong¹,

Kang

2016

Korean J Adult Nurs

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“…The effect of premedication has been mainly assessed in relation to: heart rate; blood pressure; neuroendocrine changes; quality of induction of anaesthesia; amnesia and anxiety [4]. It is important that we are aware of the impact that pre-operative anxiety may have on postoperative outcomes [5].The relationship between pre-operative anxiety and postoperative pain is of particular importance, since several pharmacological and non-pharmacological options are available to treat pre-operative anxiety [6]. If increased pre-operative anxiety is associated with increased postoperative pain, then reducing pre-operative anxiety, could reduce postoperative pain.…”

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Effect of pre‐operative anxiolysis on postoperative pain response in patients undergoing total abdominal hysterectomy

Caumo¹,

Hidalgo²,

Schmidt

et al. 2002

Anaesthesia

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SummaryIn a double blind, placebo-controlled trial, we have assessed the effects of pre-operative anxiolysis on postoperative pain scores in 112 ASA I-II women, aged 18-65 years, scheduled to undergo total abdominal hysterectomy. Subjects were randomly allocated to receive either oral diazepam 10 mg (n ¼ 56) or placebo (n ¼ 56) pre-operatively. Postoperative anxiety, pain scores, analgesic consumption, and sedation were evaluated at several time points during the first 24 h following surgery. Postoperative pain scores were found to be significantly higher in the diazepam group. Trait and state anxiety showed a significant effect on pain scores, independent of the treatment group. No difference was found between the groups in morphine consumption, but there was a significant reduction in morphine consumption with time. The association between anxiety and postoperative pain is well known [1][2][3], and despite the routine use of benzodiazepines (BZD), there is little clinical evidence available on the effects of premedication on postoperative outcomes such as pain scores and analgesic consumption. The effect of premedication has been mainly assessed in relation to: heart rate; blood pressure; neuroendocrine changes; quality of induction of anaesthesia; amnesia and anxiety [4]. It is important that we are aware of the impact that pre-operative anxiety may have on postoperative outcomes [5].The relationship between pre-operative anxiety and postoperative pain is of particular importance, since several pharmacological and non-pharmacological options are available to treat pre-operative anxiety [6]. If increased pre-operative anxiety is associated with increased postoperative pain, then reducing pre-operative anxiety, could reduce postoperative pain.Therefore, the purpose of this study was to assess the effect of pre-operative anxiolysis on postoperative pain scores based on analgesic consumption and pain scores in patients undergoing total abdominal hysterectomy. Methods

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“…Preoperatif anksiyetenin postoperatif ağrı denetiminde rol oynayan olaylar zincirinde kritik bir role sahip olduğu belirtilmiştir (41).…”

Section: Discussionunclassified

Pregabalinin lomber interlaminar epidural kortikosteroid enjeksiyonu uygulaması sonrası vizüel analog skala değerlerine etkisi

Yektaş¹,

Gümüş²,

Kerem³

et al. 2014

Ege Tıp Dergisi

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Amaç: İnterlaminar lomber epidural kortikosteroid enjeksiyonu (İLEKE) bel ağrısında kullanılan minimal invaziv bir tedavi yöntemidir. Bu çalışmada radikülopatisi olan disk hernili hastalarda İLEKE uygulamasında pregabalinin VAS değerlerine etkisini incelemeyi amaçladık.Gereç ve Yöntem: Polikliniğimize başvuran ve İLEKE uygulanan 100 hastaya ait kayıtların retrospektif olarak incelenerek hastaların pregabalin alan Grup P ve almayan Grup Z olarak iki gruba ayrılmasıyla gerçekleştirildi. Vizüel analog skala (VAS) değerleri 1. hafta, 1-6. ay ve 1. yıl da değerlendirildi. Bulgular:Grup P ve Grup Z de başlangıç VAS değerlerine göre 1. hafta, 1-6. ay ve 1. yılda VAS değerleri istatistiksel olarak anlamlı düşüktü. Grup P ile Grup Z karşılaştırıldığında 1-6. ay ve 1. yıl VAS değerleri Grup P de istatistiksel olarak anlamlı düşüktü. Grup P de işlem sonrası hasta memnuniyeti Grup Z ye göre istatistiksel olarak anlamlı yüksekti.Sonuç: Pregabalin, İLEKE uygulanan radikülopatili hastalarda VAS değerlerini uzun dönemde de anlamlı olarak düşürmekte, İLEKE uygulama sayısını azaltmakta ve işlem sonrası hasta memnuniyetini arttırmaktadır.Anahtar Sözcükler: Disk hernisi, radikülopati, interlaminar lomber epidural kortikosteroid enjeksiyonu, pregabalin. Summary Aim: Inter-laminar lumbar epidural corticosteroid injection (ILECI) is a minimally invasive treatment method that is used in low-back pain. In this study, we aimed at investigating the effect of pregabalin administration on VAS values in patients with radiculopathy who have a disk hernia following administration of ILECI. Materials and Methods:The records pertaining to 100 patients who presented to our outpatient clinic were retrospectively examined; the patients were divided into two groups: Group P, the patients who received pregabalin and Group Z, the patients who did not receive pregabalin. The visual analogue scale (VAS) scores were assessed in week 1, months 1-6 and year 1. Results:The VAS scores of Group P and Group Z in week 1, and year 1 were lower than the baseline VAS scores at a statistically significant level. Based on a comparison between Group P and Group Z, it was seen that the VAS scores in months 1-6 and year 1 were lower for Group P at a statistically significant level. The postadministration patient satisfaction in Group P was higher than Group Z at a statistically significant level. Conclusion: Pregabalin significantly reduces the VAS scores in patients with radiculopathy who have received ILECI, it also decreases the frequency of ILECI administration and increases post-administration patient satisfaction.

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Attenuation of the Preoperative Stress Response with Midazolam

Abstract: Subjects treated with midazolam preoperatively self-report improved postoperative psychological and pain recovery. However, the clinical significance of these findings is unclear at the present time.

Cited by 116 publications

References 1 publication

The Effects of Music Therapy on Anxiety, Sedation, and Stress Responses of Patients Undergoing Surgery with Spinal Anesthesia

The Effects of Music Therapy on Anxiety, Sedation, and Stress Responses of Patients Undergoing Surgery with Spinal Anesthesia

Effect of pre‐operative anxiolysis on postoperative pain response in patients undergoing total abdominal hysterectomy

Pregabalinin lomber interlaminar epidural kortikosteroid enjeksiyonu uygulaması sonrası vizüel analog skala değerlerine etkisi

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