Research is a crucial component of scientific and medical progress, generating new information and advancing healthcare knowledge. In the context of Saudi Arabia, it is essential for healthcare professionals and students to engage in research activities to stay current and improve patient care. This study explores the attitudes, knowledge, and barriers faced by healthcare professionals in Saudi Arabia regarding research analysis and writing. Method: A comprehensive literature search was conducted, focusing on English-language scientific literature published between August and September 2023, primarily through PubMed, Embase, Google Scholar, and the Saudi Digital Library. Reports written in English related to research in Saudi Arabia were considered for analysis. Result: The study identifies several barriers faced by Saudi healthcare workers in research, including issues like time constraints, lack of mentoring, and inadequate knowledge. The attitude and knowledge toward publishing research among medical residents were found to be suboptimal, with some individuals reporting low knowledge and unacceptable attitudes. Challenges such as the research approval process, heavy workloads, and gender disparities in research participation were also highlighted. Conclusion: Overcoming barriers to research and promoting a research culture is crucial for strengthening the scientific value of Saudi Arabia. By addressing the identified obstacles and implementing recommended measures, Saudi Arabia can contribute to the global research community and achieve its Vision 2030 goals, particularly in the healthcare sector.