Attitudes Toward Antipsychotics Among Outpatient Clinic Attendees With Schizophrenia

Hofer, Alex; Kemmler, Georg; Eder, Ursula; Honeder, M.; Hummer, Martina; Fleischhacker, W. Wolfgang

doi:10.4088/jcp.v63n0110

Cited by 84 publications

(93 citation statements)

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“…Previous reports from Western or African countries have revealed that subjective responses to medication were associated with side effects [29,31,32], psychopathology [18,29,[31][32][33], and employment status [29][30][31], but were independent of other sociodemographic variables or length of illness [18,[30][31][32][33][34]. In this study, however, age and gender (China) and length of illness (Japan), were significantly associated with DAI-30, but employment status showed no significant association.…”

Section: Discussioncontrasting

confidence: 68%

“…This decision would be based on the belief that Western medicine provides a rapid palliative action, whereas traditional Chinese medicine is believed to produce a slow but curative or prophylactic action [22]. We presumed that subjects in Beijing had more negative attitudes toward medication due to a higher employment rate; because employment was associated with negative attitudes toward medication in previous studies [29][30][31]. However this hypothesis was not supported by our data.…”

Section: Discussioncontrasting

confidence: 57%

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Attitudes toward taking medication among outpatients with schizophrenia: cross-national comparison between Tokyo and Beijing

Kuroda

Sun

Lin

et al. 2008

Environ Health Prev Med

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Objectives The aim of this study was to compare attitudes toward medication and associated factors for patients with schizophrenia in Japan and China. Methods Age-group matched samples were drawn from outpatients in Tokyo (N = 76) and Beijing (N = 76) according to the same inclusion/exclusion criteria. Psychotropic prescription and attitudes toward medication were measured using Drug Attitude Inventory-30 (DAI-30) and an original questionnaire regarding beliefs about psychiatric medication. Stepwise regression analysis of the DAI-30 data was performed for each group. Results Japanese subjects were prescribed significantly larger amounts of antipsychotics. Polypharmacy of antipsychotics and concurrent use of anticholinergics, anxiolytics, or hypnotics were more frequently found among subjects in Tokyo than among those in Beijing. However, subjects in Tokyo and Beijing had similar subjective responses to medication, subjective evaluation of sideeffects, and complaints about overuse of psychotropics. Subjects in Tokyo complained less about physician's overreliance on medication and were less concerned about medication cost than those in Beijing. In Tokyo, longer duration of illness and lower subjective distress caused by side effects predicted a more positive subjective response, while female gender, younger age, and lower Brief Psychiatric Rating Scale score were independently correlated with a better subjective response in Beijing. Conclusions Subjective acceptance of multiple medications is greater for patients in Japan than those in China. Determinants of subjective response to medication varied between Japan and China.

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Section: Discussioncontrasting

confidence: 68%

Section: Discussioncontrasting

confidence: 57%

Attitudes toward taking medication among outpatients with schizophrenia: cross-national comparison between Tokyo and Beijing

Kuroda

Sun

Lin

et al. 2008

Environ Health Prev Med

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“…Other studies have shown that older patients and longer duration of illness led to a higher total score on the DAI; the same conclusion was noted in another crosssectional survey of stabilized outpatients, and increasing insight into the illness over time was the reason [24,25]. Our study showed that drug attitude was not affected significantly by the duration of illness.…”

Section: Discussionsupporting

confidence: 88%

Social Interaction and Drug Attitude Effectiveness in Patients with Schizophrenia

2011

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This study aimed to explore the relationship between dosage of paliperidone and drug attitude, and also clarify the factors associated with drug attitude, using Intention-to-Treat (ITT) analysis. Three hundred thirty-one patients diagnosed with schizophrenia, who prescribed paliperidone between April 2008 and April 2009, from 10 hospitals in Taiwan were enrolled. By structural equation modeling, inpatient/outpatient status associated with occupation status, sex, and score on the Clinical Global Impression-Severity (CGIS) Scale. The score on the Personal and Social Performance (PSP) Scale associated with occupation status, inpatient/outpatient status, and the score on the CGIS Scale. The scores on the DAI-10 associated with the score on the PSP Scale and age. Good drug attitude and medication adherence significantly related to good social interaction. We should enhance the drug attitude and medication adherence of patients with schizophrenia who have poor social interaction to improve the outcome of schizophrenia.

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“…Thus, the long-term safety and tolerability of oral therapy is important as it can affect treatment adherence and long-term patient health (McCreadie 1996). For example, treatment-associated sedation can have an adverse impact on patient quality of life and social integration during longer-term treatment (Hofer et al 2002). An antipsychotic agent with a low potential for sedation may, therefore, prove a more effective long-term option in terms of overall patient outcome.…”

Section: Discussionmentioning

confidence: 99%

Intramuscular aripiprazole for the treatment of acute agitation in patients with schizophrenia or schizoaffective disorder: a double-blind, placebo-controlled comparison with intramuscular haloperidol

et al. 2006

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Attitudes Toward Antipsychotics Among Outpatient Clinic Attendees With Schizophrenia

Cited by 84 publications

References 0 publications

Attitudes toward taking medication among outpatients with schizophrenia: cross-national comparison between Tokyo and Beijing

Attitudes toward taking medication among outpatients with schizophrenia: cross-national comparison between Tokyo and Beijing

Social Interaction and Drug Attitude Effectiveness in Patients with Schizophrenia

Intramuscular aripiprazole for the treatment of acute agitation in patients with schizophrenia or schizoaffective disorder: a double-blind, placebo-controlled comparison with intramuscular haloperidol

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