“…One studies (Brauer et al, 2015;Pariente et al, 2012) analyzed twodifferent types of study design: Brauer et al (2015) used the self-controlled case series and case-control study design to investigate the association between MI risk and AP use.We found four case-control studies (Brauer et al, 2015;Nakagawa et al, 2006;Penttinen and Valonen, 1996;Thorogood et al, 1992), two case-crossover studies (Wu et al, 2015b;Lin et al, 2014), one case-case time control study (Wang, 2011), Threecohort studies (Enger et al, 2004;Hwang et al, 2014;Pariente et al, 2012;Pratt et al, 1996) and oneself-controlled case series (Brauer et al, 2015;Pariente et al, 2012). The countries where the studies had been performed were Finland, Denmark, UK, Canada, Taiwan, and USA,and the range of study enrolment periods was 1980-2012.…”