Atypical behavioral and psychiatric symptoms: neurosyphilis should always be considered

Crozatti, Lucas Lonardoni; Brito, Marcelo Houat de; Lopes, Beatriz Noele Azevedo; Campos, Fernando Peixoto Ferraz de

doi:10.4322/acr.2015.021

Cited by 17 publications

(17 citation statements)

References 15 publications

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“…The case also il lus trates that spe cific an ti bacte rial treat ment leads the pa tients to re mis sion very quickly and ef fec tively [8]. Crozatti et al (2015) re ported a case with a dif fer ent clin i cal course -the man i fes ta tion of the dis ease was of a de pres sive na ture with sui cidal thoughts and cog ni tive dis tur bances. What is also in ter est ing, is that dur ing the course of treat ment, some psy chotic symp toms, par tic u larly para noid ideation and persecutory de lu sions ap peared, which would also sup port the idea of the ex treme un pre dict abil ity of neurosyphilis.…”

Section: Discussionmentioning

confidence: 83%

Challenges of diagnostics and treatment of non-specific mental health disorders in neurosyphilis

Matuzevičius¹,

Bagdonaitė²

2019

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Sifilis nuo seno visame pasaulyje buvo itin rimta ir pavojinga liga, dažnai pasibaigianti ilgalaikiu neįgalumu ar net mirtimi. Nors sergamumas sifiliu pastaraisiais metais Lietuvoje po truputį mažėja, stacionare vis dar gydome daug pacientų, sergančių įvairiomis šios ligos formomis. Šiame straipsnyje pateikiame unikalų ir sudėtingą 52 m. moters, sergančios neurosifiliu, pasireiškiančiu itin polimorfišku klinikiniu vaizdu, atvejį. Aptariame diagnostikos ir gydymo problematiką, palyginame savo atvejį su kitų autorių patirtimi ir pateikiame savo įžvalgas šia tema.

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Section: Discussionmentioning

confidence: 83%

Challenges of diagnostics and treatment of non-specific mental health disorders in neurosyphilis

Matuzevičius¹,

Bagdonaitė²

2019

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“…Th ere are many case reports that underline the fact that appropriate treatment may be delayed due to nonspecifi c psychiatric symptoms. For instance, Costiniuk and MacPherson eported 3 patients who presented with sleep disturbances, psychosis, hyperactivity, seizures, cognitive impairment, lower-limb weakness and dysarthria 5,6 .…”

Section: Resultsmentioning

confidence: 99%

Diagnostic Challenges Arising from Neuropsychiatric Manifestations of Syphilis: Insights from 11 Clinical Cases

BRAN¹,

Ghergu²,

Davidescu³

2019

Rev. Med. Mod.

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Over the past 70 years, the incidence of syphilis has dramatically decreased and consequently the neurosyphilis one. Therefore, when a patient is presented with neuropsychiatric symptoms such as psychosis, mania, memory loss, neurocognitive troubles, attention defi cits, behavioral changes, or depression, a neurosyphilis diagnosis is not the fi rst that comes to a clinician's mind. In fact, many times, patients are fi rst treated with psychiatric medication when penicillin would be the appropriate line of treatment. In this article, after we review neurosyphilis, we report 11 clinical cases with neuropsychiatric manifestations of syphilis and make the case for careful syphilis screening in patients presenting with psychiatric and neurological symptoms.

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“…; Crozatti et al. ). More recent studies have looked at the effect of enteric bacteria on mental health.…”

Section: The Microbiome‐gut‐brain Axis and Mental Diseasementioning

confidence: 98%

The Physicalized Mind and the Gut‐brain Axis: Taking Mental Health Out of Our Heads

Bruce¹,

Ritchie²

2018

Zygon

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As it becomes increasingly plausible that the mind–brain is explicable in naturalistic terms, science‐and‐religion scholars have the opportunity to engage creatively and proactively with facets of brain‐related research that better inform our understanding of human well‐being. That is, once mental health is recognized as being a whole‐body phenomenon, exciting theological conversations can take place. One fascinating area of research involves the “gut–brain axis,” or the interactive relationship between the microbiome in the gastrointestinal tract (i.e., gut bacteria), the central nervous system, and mental health. A growing body of literature explores the immensely significant interactions between the gut microbiome and mental health issues involving depression, anxiety, gene expression, and stress responses. One's mental health does not occur in a disembodied state, but in a complex physical environment that is strongly influenced by environmental factors, many of which we can control. This article argues that science‐and‐religion can welcome scientific research in this area, creatively incorporating such insights into a theology of mental health and physical well‐being.

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Atypical behavioral and psychiatric symptoms: neurosyphilis should always be considered

Cited by 17 publications

References 15 publications

Challenges of diagnostics and treatment of non-specific mental health disorders in neurosyphilis

Challenges of diagnostics and treatment of non-specific mental health disorders in neurosyphilis

Diagnostic Challenges Arising from Neuropsychiatric Manifestations of Syphilis: Insights from 11 Clinical Cases

The Physicalized Mind and the Gut‐brain Axis: Taking Mental Health Out of Our Heads

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