Atypical fibroxanthoma mimicking amelanotic melanoma in dermoscopy

Atypical Fibroxanthoma-Like Amelanotic Melanoma: A Diagnostic Challenge

“…In particular, we describe a case of a very rare variant of melanoma with morphological characteristics similar to those of atypical fibroxanthoma. This variant has very rarely been described in the literature, with only five cases found in research published on PubMed and Medline [ 1 , 2 , 3 , 4 , 5 , 6 ]. More specifically, five cases reported by various authors have been described [ 1 , 2 , 3 , 4 ], and their findings are summarized in Table 1 .…”

In vivo reflectance confocal microscopy findings in a case of atypical fibroxanthoma

“…The dermoscopic features of AFXs reported in the literature include red and white structureless areas, shiny white structures, rainbow pattern and irregular linear or polymorphous vessels. 1,[3][4][5] Thus these dermoscopic features may also be seen also in other skin tumours, dermoscopy has a limited role in the clinical diagnosis. The literature data on in vivo reflectance confocal microscopy (RCM) findings of AFX is very limited and only includes the data of a case with a clear cell variant.…”

“…The clinical differential diagnosis of AFX includes huge number of non‐pigmented skin lesions. The dermoscopic features of AFXs reported in the literature include red and white structureless areas, shiny white structures, rainbow pattern and irregular linear or polymorphous vessels 1,3–5 . Thus these dermoscopic features may also be seen also in other skin tumours, dermoscopy has a limited role in the clinical diagnosis.…”