Atypical hyperplasia of the breast: Clinical cases and management strategies

Abstract

Atypical hyperplasia of the breast is a histopathologic lesion identifi ed incidentally on image-guided breast biopsy. It is associated with a substantial increase in lifetime risk for breast cancer. Clinicians should counsel women with atypical hyperplasia regarding risk-reducing strategies, which include preventive endocrine therapy options, enhanced surveillance imaging, and lifestyle modifi cations. In this review, we describe 5 different but common clinical case scenarios for atypical hyperplasia of the breast and review management strategies for each scenario.

Best acupuncture method for mammary gland hyperplasia: Evaluation of randomized controlled trials and Bayesian network meta-analysis

“…Although endocrine therapy is the main non-surgical measure, hormonal regulation, such as with tamoxifen and bromocriptine, is currently the main WM program for the treatment of breast hyperplasia. However, these drugs have many complications, and prolonged use can lead to endocrine and metabolic disorders, which are unsafe for patients [ 2 , 80 ]. Acupuncture is a safe and effective alternative treatment for MGH.…”

“…Mammary gland hyperplasia (MGH), also known as fibrocystic breast disease, is a non-inflammatory and non-neoplastic degenerative disease [ 1 , 2 ]. Patients with MGH experience breast pain due to the formation of breast lumps.…”

“…The efficacy of MGH was primarily assessed based on its clinical validity. Hormone levels are usually diagnosed using progesterone and estradiol as the main objective measurements, while physical signs are assessed using subjective measurements, including the size of the breast lump and the visual analog scale (VAS) [ 2 , 13 ]. However, the results of subjective self-assessment do not always agree with those of objective measures.…”

The Effectiveness and Safety of Acupuncture for Mammary Hyperplasia: A Systematic Review and Meta-Analysis

“… 6 In cases of suspicious nodules, puncture or surgical excision is employed to get tissues for pathological examination to prevent misdiagnosis and missed diagnosis. 7 While drug therapy has proven effective, it also presents drawbacks, such as gastrointestinal side effects, including abdominal pain and indigestion. 8 In contrast, acupuncture, a traditional medicine treatment modality, has emerged as a widely accepted alternative and complementary therapy in clinical practice.…”

Huddled and Preternatural- Atypical Lobular Hyperplasia

“…Tumefaction is commonly encountered within the fifth decade although no age of disease emergence is exempt. Atypical lobular hyperplasia is detected within<1% of core needle biopsies adopted for evaluating BI-RADS 4 lesions [1,2]. Atypical lobular hyperplasia may incriminate bilateral breasts wherein specific lesion localization is absent.…”