Atypical localizations of hydatid disease: Experience from a single institute

Mushtaque, Majid; Mir, Mohammad Muzaffar; Malik, Ajaz Ahmad; Arif, Sajad; Khanday, Samina A; Dar, Rayees Ahmad

doi:10.4103/1117-6806.95466

Cited by 27 publications

(1 citation statement)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Considering only the eligible studies from clinical centres reporting any cases of CE in any anatomical localization and where it was possible to separate liver, lung, from all other localizations (N = 7), liver represented 69.99% (1,441/2,059) of single organ localizations and 71.59% (1562/2,182) when considering multiple localizations [16][17][18][19][20][21][22]. In the same case series, lungs represented 19.18% (395/2,059) of single organ localizations and 20.16% (440/2,182) when considering multiple localizations.…”

Section: Results From Case-reports and Case-seriesmentioning

confidence: 99%

Primary cerebral cystic echinococcosis in a child from Roman countryside: Source attribution and scoping review of cases from the literature

Casulli,

Pane,

Randi

et al. 2023

PLoS Negl Trop Dis

View full text Add to dashboard Cite

Background Human cystic echinococcosis (CE) is a zoonotic parasitic infection caused by the larval stage of the species belonging to the Echinococcus granulosus sensu lato (s.l.) complex. Parasitic cysts causing human CE are mainly localized in the liver and in the lungs. In a smaller number of cases, larvae may establish in any organ or tissue, including the central nervous system (CNS). Cerebral CE (CCE) is rare but poses serious clinical challenges. Methods This study presents a case of CCE in a child living in the countryside near Rome (Italy), along with a comparative molecular analysis of the isolated cyst specimens from the patient and sheep of local farms. We also systematically searched the literature to summarize the most relevant epidemiological and clinical aspects of this uncommon localization. Findings The comparative molecular analysis confirmed that the infection was caused by E. granulosus sensu stricto (s.s.) (G3 genotype), and most likely acquired in the family farm. The literature search identified 2,238 cases of CCE. In 80.51% of cases, brain was the only localization and single CCE cysts were present in 84.07% of cases. Mean patients’ age was 20 years and 70.46% were children. Cyst rupture was reported in 12.96% and recurrence of CCE after treatment in 9.61% of cases. Permanent disability was reported in 7.86% of cases, while death occurred in 6.21%. In case series reporting all CE localization, CCE represented 1.5% of all CE cases. In the few reports that identified at molecular level the CCE cyst, E. granulosus s.s. was found in 40% and E. canadensis in 60% of cases. Conclusions We report a rare case of CCE and evidenced the probable local origin of infection. The proportions of CE cases with uncommon localizations and with high impact on patients’ lives have been globally neglected and should be included in the computation of the global burden of CE.

show abstract

Section: Results From Case-reports and Case-seriesmentioning

confidence: 99%

Primary cerebral cystic echinococcosis in a child from Roman countryside: Source attribution and scoping review of cases from the literature

Casulli,

Pane,

Randi

et al. 2023

PLoS Negl Trop Dis

View full text Add to dashboard Cite

show abstract

The multifaceted musculoskeletal hydatid disease

Ammar,

Riahi,

Chaabouni

et al. 2024

Skeletal Radiol

View full text Add to dashboard Cite

A rare case of spleenic hydatidosis in a buffalo: patho-morphological study

Sreedevi

Devi²,

Annapurna

et al. 2014

J Parasit Dis

View full text Add to dashboard Cite

Hydatidosis, a zoonotic disease caused by the metacestode of Echinococcus granulosus is considered an economically important disease due to the condemnation of affected visceral organs of domestic animals. The lungs and liver are the most commonly affected organs and is less frequently observed in spleen particularly in buffaloes compared to cattle. Out of 980 slaughtered buffaloes screened for hydatidosis a case of spleenic hydatidosis was noticed. A single cyst projecting from the surface of the spleen was observed. On incision clear watery fluid along with granular structures (protoscolices) escaped out. The inner surface of cyst contained thin, white, translucent membrane studded with cluster of brood capsules. Microscopic examination revealed germinal layer with protoscolices along with eosinophilic laminated layer. There was fibrous connective tissue proliferation around the laminated layer and a mild depletion of the lymphoid cells in the surrounding white follicles.

show abstract

Atypical localizations of hydatid disease: Experience from a single institute

Cited by 27 publications

References 21 publications

Primary cerebral cystic echinococcosis in a child from Roman countryside: Source attribution and scoping review of cases from the literature

Primary cerebral cystic echinococcosis in a child from Roman countryside: Source attribution and scoping review of cases from the literature

The multifaceted musculoskeletal hydatid disease

A rare case of spleenic hydatidosis in a buffalo: patho-morphological study

Contact Info

Product

Resources

About