Atypical mycobacteriosis in a cat

Abstract

View related articles Citing articles: 2 View citing articles INFECTIOUS DISEASES & PARASITOLOGY body testing. In each case the antigen used was whole organisms and known titre sera provided the positive controls.

Clinical outcome and diagnostic methods of atypical mycobacteriosis due toMycobacterium aviumssp.hominissuisin a group of captive lowland tapirs (Tapirus terrestris)

“…To our knowledge, this is the first report that describes clinical signs of an infection with the atypical mycobacterium MAH in tapirs. Unspecific symptoms such as lethargy or weight loss are described for MAH infections in horses, cats, dogs or African elephants ( Loxodonta africana ) (van Dongen et al., 1996; Greene, 2012; Haist et al., 2008; Klotz et al., 2018; Kriz et al., 2010; Wenker et al., 2018). The principal clinical outcome in other host species is dependent on the organ complex primarily affected.…”

“…Most NTM are environmental bacteria found in water, soil and dust, but they are also capable of infecting vertebrates, although the occurrence of disease seems to be related to the immune status of the host (Lécu & Ball, 2011;Nishiuchi, Iwamoto, & Maruyama, 2017) Turenne, Tortoli, Wallace, & Brown-Elliott, 2018). From the MAC, the subspecies MAH exhibits the broadest spectrum of hosts, including domesticated (pigs, dogs, cats, rabbits and horses) and wild animals (elephants), and the clinical outcome can either affect single organs only (e.g., respiratory or digestive tract), occur as disseminated disease or without any clinical signs (van Dongen et al, 1996;Eisenberg et al, 2012;Greene, 2012;Haist et al, 2008;Klotz, Barth, Baumgartner, & Hewicker-Trautwein, 2018;Kriz et al, 2010;Lécu & Ball, 2011;Thorel, Huchzermeyer, & Michel, 2001;Wenker et al, 2018). MAH is also an important pathogen for respiratory disease in humans with a worldwide increasing incidence and prevalence.…”

“…Bacteria of the family Mycobacteriaceae may cause disease in many animal species and in humans. Especially, mycobacteria of the Mycobacterium tuberculosis complex (MTC), for example M. tuberculosis or M. bovis , are of zoonotic concern (van Dongen et al., 1996). Species of mycobacteria outside the MTC are known as non‐tuberculous mycobacteria (NTM) or atypical mycobacteria (Bauerfeind et al., 2013; Greene, 2012; Lécu & Ball, 2011).…”

Disseminated Mycobacterium avium infection in a cat on long-term ciclosporin therapy and potential latent infection of an in-contact cat

“…3 The MAC group of organisms are the most likely of all of the NTM to produce disseminated disease in the cat, of which there here have been several reports. [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] Abyssinian and Siamese breeds appear to be over-represented. 4,6,8,9 Multiorgan involvement, as seen in this case, is a key feature of disseminated MAC infection, with haematogenous spread being the proposed mechanism of dissemination.…”

“…4,6,8,9 Multiorgan involvement, as seen in this case, is a key feature of disseminated MAC infection, with haematogenous spread being the proposed mechanism of dissemination. 11 Table 2 [4][5][6][7][10][11][12][13][14][15][16]18,19 and Table 3 [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] summarise the organ involvement and clinical manifestations of the previously reported cases of disseminated MAC. However, in contrast to many of these cases, and given the extent of the changes found on this cat's postmortem examination, there was more limited clinical evidence to suggest widespread dissemination in this case.…”