2002
DOI: 10.1007/s101650200013
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Atypical mycobacteriosis in two patients with rheumatoid arthritis

Abstract: We report two cases of rheumatoid arthritis (RA) with atypical mycobacteriosis. Opportunistic infections are critical complications for rheumatic diseases. The use of steroids or immunosuppressants may increase the risk of opportunistic infections. However, these reports are rare in that they demonstrate atypical mycobacterial infections as complications of RA, even though no immunosuppressive agents were used. We discuss the characteristics of atypical mycobacterial infections of the lung in RA.

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Cited by 3 publications
(2 citation statements)
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“…Most cases (85%) were caused by MAC. Through a literature search, we found five cases of pulmonary NTM occurring in Japanese RA patients who had never received biological agents: four were receiving prednisolone and/or nonbiological DMARDs and one was not receiving such medications [20–23]. Three patients were asymptomatic at the time of the development of NTM disease.…”
Section: Discussionmentioning
confidence: 99%
“…Most cases (85%) were caused by MAC. Through a literature search, we found five cases of pulmonary NTM occurring in Japanese RA patients who had never received biological agents: four were receiving prednisolone and/or nonbiological DMARDs and one was not receiving such medications [20–23]. Three patients were asymptomatic at the time of the development of NTM disease.…”
Section: Discussionmentioning
confidence: 99%
“…RA is a likely diagnosis with this possibility and serves simply as a risk factor for M. abscessus . It was suggested in several reports that RA would be associated with M. abscessus and NTM pulmonary disease in general even in the absence of treatment with immunosuppressant [11,21]. It is possible that the short use of methotrexate might have triggered this M. abscessus infection as it a rapidly growing opportunistic mycobacterial pathogen.…”
Section: Discussionmentioning
confidence: 99%