Atypical Presentation of a Case of Solitary Fibrous Tumor of the Orbit

Savino, Gustavo; Aliberti, Stefania; Colucci, Daniela; Perrotta, Vittoria; Balestrazzi, E.

doi:10.1080/01676830802675877

Cited by 14 publications

(17 citation statements)

References 10 publications

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“…Precontrast MR imaging findings and an enhancement pattern of SFT in the orbit are so similar to those of schwannoma, however, that orbital SFT is often misdiagnosed as schwannoma preoperatively. 8,9 Our results suggested that the type of TIC on DCE MR imaging and the enhancement pattern of very high-signal-intensity areas shown on T2-weighted imaging might be useful in the differentiation between SFT and schwannoma in the orbit.…”

Section: Discussionmentioning

confidence: 92%

“…It had been reported that the higher T2 signal intensity areas in schwannoma are related to thrombosis of degenerating blood vessels, hemorrhage, hyaline degeneration, and/or microcystic foci in Antoni B pattern, which could explain the lack of enhancement of these areas. 9 The markedly enhanced very high T2 signal-intensity areas in orbital SFT might be related to areas of various cellular components rather than to the cystic or necrotic foci seen in schwannoma.…”

Section: Discussionmentioning

confidence: 99%

“…7 Despite the distinct histologic and immunohistochemical appearance of SFT, its imaging appearance in the orbit has been considered nonspecific and it has often been misdiagnosed as schwannoma. 8,9 Nonetheless, the prognosis and treatment of SFT and schwannoma in the orbit are different, 2,6,[10][11][12][13][14][15] and distinguishing SFT and schwannoma in the orbit is important because SFT is a more aggressive lesion than schwannoma. SFTs are richly vascular with many dilated vessels.…”

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confidence: 99%

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Value of MR Imaging in Differentiation between Solitary Fibrous Tumor and Schwannoma in the Orbit

Zhang

Shi

Guo

et al. 2013

AJNR Am J Neuroradiol

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Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Value of MR Imaging in Differentiation between Solitary Fibrous Tumor and Schwannoma in the Orbit

Zhang

Shi

Guo

et al. 2013

AJNR Am J Neuroradiol

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“…On the other hand, precontrast MRI findings and an enhancement pattern of solitary fibrous tumor in the orbit may resemble those of schwannoma. 18 …”

Section: Discussionmentioning

confidence: 99%

Isolated schwannoma involving extraocular muscles

Yülek¹,

Demer

2016

Journal of American Association for Pediatric Ophthalmology and

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Background Progressive strabismus initially considered idiopathic may be caused by isolated schwannomas of motor nerves to extraocular muscles, detectable only on careful imaging. This study reviewed clinical experience of a referral practice in identifying schwannomas on magnetic resonance imaging (MRI). Methods We reviewed 647 cases imaged for strabismus to identify presumed cranial nerve schwannomas, identified by gadodiamide-enhanced, high-resolution surface coil orbital MRI and thin-section cranial MRI. Clinical features and management were correlated with MRI. Results Schwannomas were identified as fusiform intraneural enlargements in 8 cases: 1 affecting the trochlear nerve; 2, the abducens nerve; and 5 the oculomotor nerve. Involved muscles were atrophic. Both abducens schwannomas, 1 superior oblique, and 1 oculomotor schwannoma were subarachnoid; 3 were intraorbital, and bilateral oculomotor lesions of 1 case extended from cavernous sinus to orbit. Associated strabismus progressed for 3-17 years. Abducens schwannoma caused esotropia; trochlear schwannoma caused hypertropia and cyclotropia. Intracranial oculomotor schwannoma caused mydriasis and exotropia. Intraorbital schwannoma caused exotropia with or without hypertropia. Since lesion diameters were 3–9 mm, 6 had been previously missed on routine MRI. Conclusions Progressive, acquired strabismus may be caused by isolated cranial nerve schwannomas, representing about 1% of strabismus cases in this study, involving the oculomotor more than abducens nerve. Because most schwannomas are small and deep in the orbit, findings could be readily missed by routine imaging, leading to a possible diagnosis of idiopathic strabismus. Schwannomas should be suspected when extraocular muscles are atrophic, but the causative lesions themselves are identifiable only using targeted, high resolution MRI.

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“…These mesenchymal neoplasms are extremely rare in childhood. We found only 9 tumors classified as HPC 9-17 and 2, as STF 18,19 in patients younger than 10 years. They usually have a benign course, even though those that have cytologic atypia, necrosis, and 4 or more mitotic figures per 10 high-power fields can be locally aggressive or metastasize.…”

Section: Discussionmentioning

confidence: 94%