Atypical Presentation of Majocchi's Granuloma in an Immunocompetent Host

Parmar, Nisha V.; Asir, G. Johny; Rudramurthy, Shivaprakash M.

doi:10.4269/ajtmh.16-0493

Cited by 12 publications

(14 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, shaving the legs or pubic area, sexual contact, and occupation should also be investigated. 7 , 8 , 37 , 38 In this review, four of the patients were thought to have been in contact with an animal, suggesting that animal exposure was a predisposing factor of MG. Three of these patients had been in contact with guinea pigs. 34 , 39 , 40 Guinea pigs are often cryptic carriers, 41 and the clinician should consider the zoophilic characteristics of dermatophytes and whether the patient has a pet or is in frequent contact with animals.…”

Section: Source Of Infection and Possible Predisposing Factorsmentioning

confidence: 87%

“…floccosum were also reported. 7 , 8 , 10 , 35 , 49 , 66 In this review, the most common fungal isolate was T . rubrum (n=15), followed by T .…”

Section: Laboratory Diagnosismentioning

confidence: 96%

“…Although ketoconazole was frequently used previously, about half of the patients reported today are treated with terbinafine (250 mg/day). 8 , 13 , 36 , 40 , 43 , 47 , 54 , 68 – 71 Other systemic antifungal drugs are itraconazole (100–200 mg/day), 32 , 44 , 53 , 72 griseofulvin (250–500 mg/day), 10 , 35 , 63 voriconazole, 73 and posaconazole. 28 Antifungal therapy should be continued until the lesions are completely resolved.…”

Section: Treatmentmentioning

confidence: 99%

See 2 more Smart Citations

Majocchi’s granuloma: current perspectives

Boral¹,

Durdu²,

İlkit³

2018

IDR

View full text Add to dashboard Cite

Majocchi’s granuloma (MG) is a rare fungal infection of the dermis that is mainly caused by dermatophytes (in ≥95% of cases); the most frequently identified cause is anthropophilic Trichophyton rubrum. In the rest of the cases, the causes are non-dermatophytic fungi such as Aspergillus species. This review aimed to provide information about the current perspectives on MG regarding its clinical characteristics, predisposing factors, laboratory diagnosis, and treatment strategies. Although the lower extremities were reported to be the most common site of infection, facial involvement has been predominant in the past 5 years. Our literature research showed that the most common predisposing factor (55%) is the use of topical steroid creams without potassium hydroxide examination during treatment of erythematous squamous dermatoses. A reliable diagnosis of MG is based on histopathological examination, including fungal culture and molecular analyses. MG should be treated not only with topical agents but also with systemic antifungal agents that are continued until the lesions are completely resolved. In systemic treatment, the most preferred drug is terbinafine, because of its efficacy, side effects, and safety.

show abstract

Section: Source Of Infection and Possible Predisposing Factorsmentioning

confidence: 87%

“…floccosum were also reported. 7 , 8 , 10 , 35 , 49 , 66 In this review, the most common fungal isolate was T . rubrum (n=15), followed by T .…”

Section: Laboratory Diagnosismentioning

confidence: 96%

Section: Treatmentmentioning

confidence: 99%

See 1 more Smart Citation

Majocchi’s granuloma: current perspectives

Boral¹,

Durdu²,

İlkit³

2018

IDR

View full text Add to dashboard Cite

show abstract

“…There are no consensus guidelines for the treatment of Majocchi's granuloma. Some dermatologists recommend oral antifungal agents such as terbinafine or itraconazole and the duration of therapy should be at least 4-8 weeks and should be continued until all lesions are resolved [3,8]. This case is being reported as it demonstrates the atypical location of Majocchi's granuloma in the forearm of an immunocompetent host, who had been successfully treated with local moxibustion and oral itraconazole.…”

Section: Discussionmentioning

confidence: 96%

Majocchi’s granuloma on the forearm caused by Trichophyton tonsurans in an immunocompetent patient

Zheng

Chen

et al. 2020

Ann Clin Microbiol Antimicrob

View full text Add to dashboard Cite

Majocchi's granuloma is an uncommon fungal infection of the dermis and subcutaneous tissue. The most frequently identified cause of Majocchi's granuloma is anthropophilic Trichophyton rubrum, and it is most commonly located on the anterior aspect of the lower limbs in women. Here, we report a case of Majocchi's granuloma on the forearm, a site that is rarely involved, in a 62-year-old woman who had been bitten by a dog. Histological examination revealed a dense dermal infiltrate composed of lymphoplasmacytic cells and neutrophils, with hyphae in the dermis. The presence of the fungus, Trichophyton tonsurans, was confirmed by mycological examination and molecular methods. Therefore, histological and mycological examination confirmed the diagnosis of Majocchi's granuloma. The patient was treated with local moxibustion and itraconazole, 200 mg/day, for 60 days, which facilitated a complete resolution of the lesions.

show abstract

“…There are no consensus guidelines for the treatment of Majocchi's granuloma. Some dermatologists recommend oral antifungal agents such as terbina ne or itraconazole and the duration of therapy should be at least 4-8 weeks and should be continued until all lesions are resolved (3,8). This case is being reported as it demonstrates the atypical location of Majocchi's granuloma in the forearm of an immunocompetent host, who had been successfully treated with local moxibustion and oral itraconazole.…”

Section: Discussionmentioning

confidence: 96%

Majocchi’s Granuloma on the Forearm Caused by Trichophyton tonsurans in an Immunocompetent Patient

Zheng¹,

Li²,

Chen³

et al. 2020

Preprint

View full text Add to dashboard Cite

Majocchi's granuloma is an uncommon fungal infection of the dermis and subcutaneous tissue. The most frequently identified cause of Majocchi’s granuloma is anthropophilic Trichophyton rubrum, and it is most commonly located on the anterior aspect of the lower limbs in women. Here, we report a case of Majocchi’s granuloma on the forearm, a site that is rarely involved, in a 62-year-old woman who had been bitten by a dog. Histological examination revealed a dense dermal infiltrate composed of lymphoplasmacytic cells and neutrophils, with hyphae in the dermis. The presence of the fungus, Trichophyton tonsurans, was confirmed by mycological examination and molecular methods. Therefore, histological and mycological examination confirmed the diagnosis of Majocchi’s granuloma. The patient was treated with local moxibustion and itraconazole, 200 mg/day, for 60 days, which facilitated a complete resolution of the lesions.

show abstract

Atypical Presentation of Majocchi's Granuloma in an Immunocompetent Host

Cited by 12 publications

References 5 publications

Majocchi’s granuloma: current perspectives

Majocchi’s granuloma: current perspectives

Majocchi’s granuloma on the forearm caused by Trichophyton tonsurans in an immunocompetent patient

Majocchi’s Granuloma on the Forearm Caused by Trichophyton tonsurans in an Immunocompetent Patient

Contact Info

Product

Resources

About

Atypical Presentation of Majocchi's Granuloma in an Immunocompetent Host

Cited by 12 publications

References 5 publications

Majocchi&rsquo;s granuloma: current perspectives

Majocchi&rsquo;s granuloma: current perspectives

Majocchi’s granuloma on the forearm caused by Trichophyton tonsurans in an immunocompetent patient

Majocchi’s Granuloma on the Forearm Caused by Trichophyton tonsurans in an Immunocompetent Patient

Contact Info

Product

Resources

About

Majocchi’s granuloma: current perspectives

Majocchi’s granuloma: current perspectives