Atypical presentation of molar pregnancy

Langhe, Ream; Muresan, Bogdan Alexandru; Akpan, Etop; Wahab, Nor Azlia Abdul

doi:10.1136/bcr-2018-225545

Cited by 3 publications

(3 citation statements)

References 11 publications

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“…Molar pregnancy is characteristically observed as an enlarged uterus containing a hyperechoic, solid, heterogenous mass, with multiple cystic spaces representing dilated, hydropic villi. Bilateral ovarian theca lutein cysts are present in 30-50% of cases [8]. The most peculiar biologic characteristic of trophoblasts is their ability to erode maternal tissue.…”

Section: Discussionmentioning

confidence: 99%

Rare Case of a Young Female With Co-existent Hydatidiform Mole and Pulmonary Metastases: An Underrecognized Entity

Ravikanth¹

2021

Cureus

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Gestational trophoblastic disease (GTD) comprises placental-site hydatidiform moles, invasive moles, or choriocarcinoma which are of unknown etiology and characterized by abnormal proliferation of gestational trophoblastic tissue. Furthermore, malignant GTD is also characterized by hematogenous spread to distant metastatic sites. Nevertheless, early diagnosis of gestational trophoblastic disease is important to ensure timely and successful management of the clinical condition and for the preservation of fertility. We report the unusual case of a complete hydatidiform mole to pulmonary metastases in a 27-year-old woman with elevated beta-human chorionic gonadotropin (β-hCG) levels. The placental histopathology showed a complete hydatidiform mole with absent fetal parts. Beta-human chorionic gonadotrophin (β-hCG) levels were found elevated at 893 mIU/mL. The case was discussed at the multidisciplinary tumour board and surgical resection with four cycles of combination chemotherapy was recommended, following which β-hCG normalization was achieved. This case report highlights the importance of clinical vigilance even in low-risk patients. Unexpected findings on ultrasound should involve multidisciplinary input from radiologists and surgical oncologists. A high index of suspicion for gestational trophoblastic disease and imaging follow-up for metastases is imperative.

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Section: Discussionmentioning

confidence: 99%

Rare Case of a Young Female With Co-existent Hydatidiform Mole and Pulmonary Metastases: An Underrecognized Entity

Ravikanth¹

2021

Cureus

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“…Blood samples were collected (2-3 mL) by venipuncture in glass tubes inside Gel Tube for separated using a disposable syringe. After (15) minutes at room temperature, the tubes were centrifuged for (10) minutes at (1500xg). The buffy coat was removed and Serum samples were stored at (−20°C) until used.…”

Section: Methodsmentioning

confidence: 99%

“…Preeclampsia can progress to eclampsia, which is marked by extreme hypertension and convulsions and can lead to coma and death if left untreated [8]. Other serious complications can be considered a life threatening condition for the mother and the fetus involve ectopic pregnancy (implantation of the embryo outside the uterine) [9], molar pregnancy (over growth of chorionic fetal tissues inside the uterine) [10], hemostasis (thrombosis) [11] and gestational diabetes mellitus, which is characterized by hyperglycemia as a result of ________________________________________________ Egypt. J. Chem.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Protein Oxidation Parameters in Women with Pregnancy Complications

Alwahab

Zainal

2021

Egypt. J. Chem.

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Pregnancy is a physiological condition start from fertilization to delivery. The mother and the fetus are exposed to serious complications during pregnancy. Variations in the antioxidant protection mechanism characterize this condition. The aim of this study was to estimate serum ceruloplasmin activity (Cp) and some biochemical parameters levels as markers of oxidative stress in serum of women with pregnancy complications compared to women with healthy pregnancies as control group and study the correlation between them. The study included (70) serum samples divided into (45) samples as patients with pregnancy complications which are sub-divided to the following groups: preeclampsia, anemia and Abortion and (25) samples of women with healthy control group. All of the studied groups showed non-significant difference in total protein level and ceruloplasmin activity except abortion group which had a significant decrease when compared to other groups. All studied groups showed non-significant differences in free amino, thiol and carbonyl levels, while abortion group showed significant decrease in carbonyl levels. In addition, all of the studied groups showed a non-significant increase in copper (Cu) levels, except for abortion group, that showed a significant decrease. Finally, all of the studied groups showed a non-significant increase in iron (Fe) levels, except the preeclampsia group, that showed a significant increase as compared to other groups.

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A Complete Hydatidiform Mole Complicated by Theca Lutein Cysts in a Teenager: A Rare Case

Potdar,

Dahiphale

2024

Cureus

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A hydatidiform mole (HM), often known as molar pregnancy, is a type of prenatal trophoblastic illness that develops in the placenta and has the potential to spread. HMs are caused by genetic issues with either the egg or the sperm. They are typically discovered in the first trimester of pregnancy. Abnormal bleeding is one of the initial symptoms, which can seldom be accompanied by the passage of hydropic villi. Theca lutein cysts, absent fetal heart tones, enlarged uterus more than anticipated for gestational age, pregnancy-induced hypertension in the first trimester, hyperemesis, and increased levels of human chorionic gonadotropin (HCG) for gestational dates are other characteristic symptoms and signs. A rare type of follicular cyst known as a theca lutein cyst is a benign ovarian disease caused by natural overstimulation of follicles, also known as hyperreactio lutealis (HL). This is linked to choriocarcinomas, multiple gestations, and prenatal trophoblastic illness (molar pregnancy). Unless exacerbated by torsion, rupture, or bleeding, the majority of theca lutein cysts are treated conservatively. Theca lutein cysts do not impact the course of pregnancy and spontaneously recede following delivery. However, HL may mistakenly be diagnosed by doctors as a cancer during pregnancy if it has the potential to look like one. Frequently, inappropriate surgical intervention is caused by the fear of failing to diagnose malignancy. These treatments may therefore result in decreased fertility in the future. Here we present a case of a young unmarried female with an HM and cysts.

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Atypical presentation of molar pregnancy

Cited by 3 publications

References 11 publications

Rare Case of a Young Female With Co-existent Hydatidiform Mole and Pulmonary Metastases: An Underrecognized Entity

Rare Case of a Young Female With Co-existent Hydatidiform Mole and Pulmonary Metastases: An Underrecognized Entity

Evaluation of Protein Oxidation Parameters in Women with Pregnancy Complications

A Complete Hydatidiform Mole Complicated by Theca Lutein Cysts in a Teenager: A Rare Case

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