Atypical Presentations of Sinonasal Inverted Papilloma: Surgical Management and Influence on the Recurrence Rate

Abstract

Recurrence rates for these atypical presentations arise from their specific surgical challenges. The choice of the surgical technique is guided by tumor location and extension, and by the surgeon's experience; the main objective is a complete resection. The endoscopic endonasal approach is the most frequent procedure.

Use of Intraoperative Negative Margins Reduces Inverted Papilloma Recurrence

“…When reviewing recent systematic meta-analyses and large cohort studies, the IP recurrence rates ranged from 12 to 17%. 4,13 Our recurrence rates seemed to be superior to contemporary reports available in the literature. There were several limitations to our study.…”

Combination of serum squamous cell carcinoma antigens 1 and 2 as potential diagnostic marker for sinonasal squamous cell carcinoma and inverted papilloma

“…1 The incidence of SCC associated with inverted papillomas ranges from 2%-27% in the literature. Although inverted papilloma is a rare benign tumor, it can invade the lacrimal system, the orbit, or the intracranial cavity and destroy bone and soft tissue.…”

“…In addition, inverted papilloma has a high propensity for local recurrence and may undergo malignant transformation into squamous cell carcinoma (SCC). 1 The incidence of SCC associated with inverted papillomas ranges from 2%-27% in the literature. 2 In general, preoperative patients with nasal tumors, including inverted papilloma and SCC, are examined via nasal endoscopy, CT, and MRI.…”

Need for long‐term follow‐up in sinonasal inverted papilloma: A Single‐institution experience

“…Previous series reported a rate of approximately 2:1 of synchronous to metachronous transformation 22 . Treatment of SNIPs primarily consists of surgical tumor resection, with an endonasal‐endoscopic approach being considered as gold standard 15,27‐31 . For SNIP follow‐up and post‐treatment surveillance, certain authors recommended postoperative surveillance for 2 to 5 years, while others opted for a lifetime follow‐up 14,18,20,32‐35 …”