2002
DOI: 10.1136/vr.151.1.21
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Atypical time course of clinical signs in a dog poisoned by strychnine

Abstract: The general health of a German shepherd dog had deteriorated slightly when it was found after being loose for one hour. After 10 hours of observation, the dog showed signs of pain for the first time and signs of poisoning, such as tenseness of muscles, slight opisthotonus, regurgitation, salivation, mydriasis, dyspnoea and cyanosis, were observed; it died 15 minutes after showing the first clinical signs but it had no seizures or tetanic spasms at any time. A postmortem examination did not reveal any pathologi… Show more

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Cited by 5 publications
(2 citation statements)
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“…Other known drugs and toxins that have the potential to cause hyperlactatemia include: nucleoside HIV reverse transcriptase inhibitors, 240 the biguanide anti-hyperglycemic agents (phenformin, metformin), 16,145,146,[292][293][294][295] linezolid, 240,[296][297][298] isoniazid, 240,299,300 5-fluorouracil, 301,302 the sugar alcohols fructose, sorbitol, and xylitol, 29,268,[303][304][305] as well as acetylcholinesterase inhibitor and carbamate pesticides. [306][307][308][309][310]…”
Section: Miscellaneousmentioning
confidence: 99%
“…Other known drugs and toxins that have the potential to cause hyperlactatemia include: nucleoside HIV reverse transcriptase inhibitors, 240 the biguanide anti-hyperglycemic agents (phenformin, metformin), 16,145,146,[292][293][294][295] linezolid, 240,[296][297][298] isoniazid, 240,299,300 5-fluorouracil, 301,302 the sugar alcohols fructose, sorbitol, and xylitol, 29,268,[303][304][305] as well as acetylcholinesterase inhibitor and carbamate pesticides. [306][307][308][309][310]…”
Section: Miscellaneousmentioning
confidence: 99%
“…It produces tetanic spasms that are exacerbated by auditory or tactile stimuli. 93 The toxic dose in most animals ranges from 0.3 to 1.0 mg/kg with the lethal dose being 2.0 mg/kg in cats. 91 This may simply reflect a greater likelihood of exposure in such dogs.…”
Section: Toxic Cause Of Tetany: Strychninementioning
confidence: 99%