Atypical virulence of Leptospira kirschneri serogroup Icterohaemorrhagiae isolated from capybaras (Hydrochoerus hydrochaeris) in hamster model

Immune response at a vaccine-challenge study using beagle dogs and locally isolated Leptospira spp

“…There was 3+ positive for leptospiral bacterial loads after serial dilution (1:10, 1:100 and 1:100) from the kidney cultures. Cultures from the liver and lung were negative for Leptospira spp., demonstrating the non-systemic nature of the disease in this study, which could have accounted for the lack of clinical manifestations (Barbosa et al, 2019), whereas the culture from the kidneys was positive, suggesting the presence of the renal carriage state or chronic infection.…”

Infectivity and virulence of leptospiral strains of serogroup Sejroe other than Hardjo on experimentally infected hamsters

“…Female golden Syrian hamsters (Mesocricetus auratus) 6-8 weeks of age and 80-120 g in weight were purchased from breeding facilities, housed in ventilated racks, and submitted to an adaptation period of 72 h prior to the tests at a temperature of 20-22°C, a light/dark photoperiod, access to feed and water ad libitum, and an enriched environment. All procedures occurred under a biosafety cabinet [17].…”