Atypisches Fibroxanthom am Capillitium

Abstract

Atypical fibroxanthoma (AFX) is a rare, low-malignant, mesenchymal tumor of the dermis and is assigned to the group of fibrohistiocytic tumors. The tumor occurs especially in photodamaged skin on the scalp of elderly men. A clinical diagnosis is not possible due to a multitude of possible differential diagnoses (leiomyosarcoma, squamous cell carcinoma, spindle cell malignant melanoma, dermatofibrosarcoma protuberans). Immunohistochemical and histological examinations should be performed to confirm the diagnosis. The tumor shows a very good prognosis after complete excision. Micrographically controlled surgery is considered as the treatment of choice.

Electronic brachytherapy management of atypical fibroxanthoma: report of 8 lesions

“…These metastatic tumors histologically resemble AFX, but may represent misdiagnosis and may conceal a more aggressive neoplasm, such as squamous cell carcinoma, malignant melanoma, or MFH [3]. A PubMed search to 1970 disclosed no literature on the use of radiation therapy as primary treatment for AFX, and no contraindication to the use of radiations for AFX [2, 6, 10, 11]. Because of the lack of contraindication to the use of radiations in the literature, we elected to treat AFX with electronic brachytherapy.…”