[Au(Et2dtc)2][TcNCl4] - Darstellung und Struktur

Abram, Ulrich

doi:10.1002/(sici)1521-3749(200003)626:3<619::aid-zaac619>3.0.co;2-t

Cited by 5 publications

(3 citation statements)

References 7 publications

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“…Bis(dithiocarbamate) complexes, [Au(S 2 CNR 2 ) 2 ] + (Fig. 9b) are easily prepared upon addition of two equivalents of dithiocarbamate salts to gold(III) halides or oxidativeaddition of thiuram disulfides to gold(I) halides [84] and contain a square-planar d 8 metal center akin to that found in analogous copper(III) complexes. Unlike the latter, which do not react with further dithiocarbamate, a third equivalent of dithiocarbamate adds to form [Au(S 2 CNR 2 ) 2 ] 3 (Fig.…”

Section: Gold Chemistrymentioning

confidence: 99%

Metal-dithiocarbamate complexes: chemistry and biological activity

Hogarth¹

2012

MRMC

255

157

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Dithiocarbamates are highly versatile mono-anionic chelating ligands which form stable complexes with all the transition elements and also the majority of main group, lanthanide and actinide elements. They are easily prepared from primary or secondary amines and depending upon the nature of the cation can show good solubility in water or organic solvents. They are related to the thiuram disulfides by a one-electron redox process (followed by dimerisation via sulfur-sulfur bond formation) which is easily carried out upon addition of iodide or ferric salts. Dithiocarbamates are lipophilic and generally bind to metals in a symmetrical chelate fashion but examples of other coordination modes are known, the monodentate and anisobidentate modes being most prevalent. They are planar sterically non-demanding ligands which can be electronically tuned by judicious choice of substituents. They stabilize metals in a wide range of oxidation states, this being attributed to the existence of soft dithiocarbamate and hard thioureide resonance forms, the latter formally resulting from delocalization of the nitrogen lone pair onto the sulfurs, and consequently their complexes tend to have a rich electrochemistry. Tetraethyl thiuramdisulfide (disulfiram or antabuse) has been used as a drug since the 1950s but it is only recently that dithiocarbamate complexes have been explored within the medicinal domain. Over the past two decades anti-cancer activity has been noted for gold and copper complexes, technetium and copper complexes have been used in PET-imaging, dithiocarbamates have been used to treat acute cadmium poisoning and copper complexes also have been investigated as SOD inhibitors.

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Section: Gold Chemistrymentioning

confidence: 99%

Metal-dithiocarbamate complexes: chemistry and biological activity

Hogarth¹

2012

MRMC

255

157

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“…250 An unusual ligand exchange and redox reaction occurred when [Au(CO)Cl] and [TcN(S 2 CNEt 2 ) 2 ] reacted to give [Au(S 2 CNEt 2 ) 2 ][TcNCl 4 ]. 251 Adding phen•HCl to HAuCl 4 gave planar [AuCl 2 (phen)]Cl. NMR ( 1 H) spectroscopy showed its aqueous solutions lost chloride within 30 min but [Au(phen)] 3+ seemed to be stable under physiological conditions and is cytotoxic to at least one human tumour cell line, but its ready reduction by ascorbate hints that the cytotoxicity might be attributed to the reductive release of phen.…”

Section: High Oxidation Statesmentioning

confidence: 99%

Untitled

Thornton¹

2001

Annu. Rep. Prog. Chem., Sect. A

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“…Among the heavier coinage metals, well-defined mononuclear homoleptic dithiocarbamate complexes are known for trivalent gold, including complexes of the types [Au(DTC) 3 ] and [Au(DTC) 2 ] + (DTC = dithiocarbamate) . While a strongly preferred square-planar coordination for the cationic bis(DTC) complexes has been proven by single-crystal structural analyses (Scheme b), − data on the molecular structures of tris(DTC) complexes are scarce. The saltlike compound [Au(H 2 L) 2 ]Cl ( 6 ) has been prepared and studied regarding its DNA and protein binding ability by K asalović et al In this contribution, we investigated the bis(DTCC) metalloligands [Cu II (L) 2 ] 4– and [Au III (L) 2 ] 3– , and their ability to form well-defined heterobimetallic CNs as exemplified with Sr 2+ ions as the oxophilic metal component.…”

Section: Introductionmentioning

confidence: 99%

Expanding the Library of Dithiocarbamato-Carboxylate Metalloligands for Heterobimetallic Coordination Networks toward Copper and Gold

Behling,

Kintzel,

Heinrich

et al. 2023

Crystal Growth & Design

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With [Cu(L)2]4– and [Au(L)2]3– (L = N-dithioato-iminodiacetate), two new potentially useful metalloligands for the construction of heterobimetallic coordination networks (CNs) were investigated. As compared to other metal(II) bis(DTCC) metalloligands (DTCC = dithiocarbamato carboxylate), the Cu(II) complexes are structurally more diverse and enable potentially interesting redox and magnetic properties. Au(III) forms structurally related bis(DTCC) complexes and allows for the construction of new coordination-polymeric assemblies due to its +3 charge. The preparation of heterobimetallic coordination networks was demonstrated with Sr2+ ions as a representative example, thus obtaining the products Sr2[Cu(L)2], Sr3[Au(L)2]2, and Sr5(OAc)[Au(L)2]3, in the form of well-defined hydrates. For comparison purposes, the group-10 analogs Sr2[Ni(L)2] and Sr2[Pd(L)2] were also prepared. The products were characterized by thermal, spectroscopic, electrochemical, and X-ray diffraction methods.

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[Au(Et2dtc)2][TcNCl4] - Darstellung und Struktur

Cited by 5 publications

References 7 publications

Metal-dithiocarbamate complexes: chemistry and biological activity

Metal-dithiocarbamate complexes: chemistry and biological activity

Untitled

Expanding the Library of Dithiocarbamato-Carboxylate Metalloligands for Heterobimetallic Coordination Networks toward Copper and Gold

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