AU-Night Sleep Polygraphic Recordings of Healthy Aged Persons: REM and Slow-Wave Sleep

Hayashi, Yasushi; Endo, Shiro

doi:10.1093/sleep/5.3.277

Cited by 76 publications

(22 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Vogel et a1. (24), in discussing a more pronounced "leftward shift" of REM sleep (i.e., increase in early REM percent) in patients with endogenous depression, hypothesizes diminished REM sleep inhibition with increasing age (as well as with depression), a concept also espoused by Hayashi and Endo (12) and more recently by Beersma et a1. (25).…”

Section: Discussionmentioning

confidence: 93%

Sleep of Healthy Seniors: A Revisit

Reynolds

Kupfer

Taska

et al. 1985

Sleep

121

View full text Add to dashboard Cite

Summary: In an EEG sleep study of 40 healthy seniors (19 men and 21 women) aged 58-82 years, men could not maintain sleep as well as women and experienced less stage 3 sleep. The increased wakefulness after sleep onset among the men was particularly marked during the last 2 h of recording. REM density (during the first and second REM periods) showed an interaction of sex and age effects: thus, women in their 60s had higher REM density than men, whereas men in their 70s had higher REM density than women. In both men and women, however, regardless of age, the temporal distribution of REM sleep and REM density during the night was flat. Finally, only a mild degree of sleep-disordered breathing was noted, with positive age effects on apnea/hypopnea index and maximal duration of apnea. These findings are reviewed in relation to the sleep and aging literature. Key Words: Sleep-Aging-Healthy e1derly-Apnea-Slow-wave sleep-REM sleep.Although the effects of age on sleep are generally well described [for review, see Miles and Dement (1) or Spiegel (2)], actual electroencephalographic (EEG) sleep norms for the 7th and 8th decades of life are still somewhat sparse in the world literature. Thus, we estimated a total of 150 elderly subjects in the studies of Lairy et al. (13), and Principe and Smith (14). In addition to the relatively modest size of the database, very little data on phasic REM activity in healthy seniors have been published to date. To some extent also, the issue of gender-dependent differences in measures of sleep continuity, slow-wave sleep, and phasic REM activity may not be completely settled. Hayashi and Endo (12) noted no differences in the sleep of healthy elderly men and women, whereas Williams et al. (10) reported better sleep continuity and more slow-wave sleep in women.Given the increasing application of all-night EEG sleep studies for clinical and research purposes, the relatively small number of elderly subjects in the world literature, and the need for further examination of age and sex effects (and their interaction) on measures of sleep continuity, slow-wave sleep, and phasic REM activity, efforts to replicate and to add

show abstract

Section: Discussionmentioning

confidence: 93%

Sleep of Healthy Seniors: A Revisit

Reynolds

Kupfer

Taska

et al. 1985

Sleep

121

View full text Add to dashboard Cite

show abstract

“…Average values for sleep latency in normal subjects have been reported to range from about 8 min to as high as 40 min (Brezinova, 1975; Feinberg, Koresko, & Heller, 1967;Hayashi & Endo, 1982;Kahn & Fisher, 1969;Kahn, Fisher, & Lieberman, 1970;Kales, Jacobson, Kales, Kun, & Weissbuch 1967a;Kales, Wilson, Kales, Jacobson, Paulson, Kollar, & Walter 1967b;Monroe, 1967;Prinz, 1977;Prinz, Peskind, Vitalino, Raskind, Eisdorfer, Zemcuznikov, & Cerber, 1982;Webb, 1982). Specifically, wake time after sleep onset, number of nocturnal awakenings, and both the average duration of these awakenings and final awakenings were all greatest in the oldest age group.…”

Section: Discussionmentioning

confidence: 99%

Nocturnal Sleep and Wakefulness: Effects of Age and Sex in Normal Sleepers

Bixler

Kales

Jacoby

et al. 1984

International Journal of Neuroscience

View full text Add to dashboard Cite

Sleep patterns were evaluated in 100 normal men and women who did not have any complaints of a sleep disorder and who were divided into three broad age groups: 19-29, 30-49, and 50-80 years. Total laboratory recording time was held constant across all four study nights. The amount of nightly wakefulness was positively correlated with age; total wake time for the oldest age group was about two times that of the youngest group, due primarily to an increase in wake time after sleep onset, because sleep latency did not change with age. Within each of the three age groups, especially the two oldest groups, the greatest amount of wakefulness following sleep onset occurred in the final hours of the recording period. Sleep in men was characterized by a higher number of nocturnal awakenings, and in elderly men by a longer final awakening; however, other parameters of sleep efficiency did not differ considerably between the sexes.

show abstract

“…Consistent with the transition to a morning chronotype in older adult humans, the circadian phase of sleep onset and wakening advances with age, whereby older adults (mean age of 68 years) report preferred bedtimes 1 to 2 hours earlier, on average, compared with younger adults (mean age of 23 years) (34,35). Older adults experience significantly more wakenings, have longer latencies to fall asleep, and spend less time in stage 3, stage 4, and rapid eye movement (REM) sleep compared with younger adults (18,(36)(37)(38). Similar observations of sleep fragmentation have been made in aged rhesus monkeys (38), hamsters (39), and Drosophila (40).…”

Section: Age-associated Changes In Circadian Rhythmsmentioning

confidence: 99%