AuCl3-catalyzed synthesis of (E/Z)‒chloroallyl carbazoles via a cascade cyclization process

Abstract

An efficient, one pot, high yielding method for the formation of (E/Z)-chloroallyl carbazoles has been developed. The strategy involves a gold-catalyzed cascade cyclization and hydroamination reaction sequence, leading to the formation of new C-C, C-N and C-Cl bonds.

Gold-catalyzed reactions using N-propargyl β-enaminones

“…As part of our ongoing interest in gold catalysis, [25][26][27][28] we are interested in reviewing the gold-catalyzed reactions of substituted enaminones. The products achieved throughout this process are versatile building blocks for many heterocyclic molecules.…”