Audio-vestibular evaluation in patients with essential tremor

Balaban, Hatice; Altuntaş, Emine Elif; Uysal, İsmail Önder; Şentürk, İlteriş Ahmet; Topaktaş, Suat

doi:10.1007/s00405-011-1801-x

Cited by 13 publications

(9 citation statements)

References 16 publications

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“…The otoacoustic emission responses were abnormal in more cases than controls while the latencies of waves I, V and I–V inter-peak latencies on the brainstem auditory evoked response did not differ between patients and controls. The authors concluded that the observed sensorineural hearing loss was due to cochlear rather than the retro-cochlear pathology [20]. The difference in the age of the patients could explain the different audiometric results between the two studies.…”

Section: Resultsmentioning

confidence: 99%

Non-motor symptoms in essential tremor: A review of the current data and state of the field

Louis

2016

Parkinsonism & Related Disorders

136

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Background The motor features of essential tremor (ET) include its hallmark element, kinetic tremor, yet non-motor features are increasingly being recognized as an accompanying part of what was previously viewed as a solely motor disorder. Given the evolving state of the ET field with respect to these non-motor features, the purpose of this manuscript is to critically review the current data. Methods A PubMed search was conducted on July 1, 2015. The term “essential tremor” was crossed in sequential order with 13 additional search terms (e.g., “cognitive”, “dementia”, “depression”). The total number of unique hits was 322. Results Numerous studies seem to substantiate the presence of a range of non-motor features occurring in excess in ET cases compared to age-matched controls. These comprise cognitive features (including a full spectrum from mild cognitive difficulty through to frank dementia), psychiatric (including depression, apathy, anxiety, and personality characteristics), sensory (hearing and possibly olfactory abnormalities), and other non-motor features (e.g., sleep dysregulation). Emerging evidence suggests that some of these features could be primary disease features that pre-date motor features of ET. Conclusions The presence of numerous non-motor features in ET is increasingly evident. The biological basis of these features deserves additional study.

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Section: Resultsmentioning

confidence: 99%

Non-motor symptoms in essential tremor: A review of the current data and state of the field

Louis

2016

Parkinsonism & Related Disorders

136

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“…Audiology testing shows high frequency sensorineural hearing loss in essential tremor patients 50. The average hearing thresholds at 250-500 Hz are higher in patients with essential tremor 51…”

Section: Clinical Manifestationsmentioning

confidence: 99%

Essential tremor: diagnosis and management

Shanker

2019

BMJ

117

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Essential tremor is one of the most common movement disorders in adults and can affect both children and adults. An updated consensus statement in 2018 redefined essential tremor as an isolated action tremor present in bilateral upper extremities for at least three years. Tremor may also be present in other locations, commonly the neck or the vocal cords. Patients with additional neurologic symptoms are now categorized as “essential tremor plus.” Additional clinical features associated with the condition include but are not limited to cognitive impairment, psychiatric disorders, and hearing loss. When treatment is needed, propranolol and primidone are considered first line treatments. Patients who are severely affected are often offered deep brain stimulation. Although the ventral intermediate nucleus of the thalamus is the traditional surgical target, the caudal zona incerta is also being studied as a possible superior alternative. Magnetic resonance imaging guided high intensity focused ultrasound is a newer surgical alternative that may be ideal for patients with substantial medical comorbidities. Current research explores novel oral treatments, chemodenervation, and noninvasive neuromodulation for treatment of essential tremor.

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“…ABR was not different between groups. They concluded that the abnormalities are due to the cochlea rather than an auditory brainstem pathway pathology, which is responsible for hearing loss associated with ET [42]. Yilmaz et al evaluated sensorineural hearing loss by PTA, speech recognition threshold, tympanogram, SISI, tone decay, and otoacoustic emission audiological tests in non-depressed subjects.…”

Section: Hearing Impairment and Essential Tremormentioning

confidence: 99%

Auditory and Olfactory Deficits in Essential Tremor – Review of the Current Evidence

Şengül

2020

Tremor and Other Hyperkinetic Movements

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Background: Essential tremor (ET) is the most common adult movement disorder, characterized by several motor and increasingly well recognized non-motor symptoms. Sensory deficits, such as hearing impairment and olfactory dysfunction, are amongst them. This review analyzes the available evidence of these sensory deficits and their possible mechanistic basis in patients with ET. Method: A PubMed literature search on the topic was performed in the May 2019 database. Results: Nineteen articles on hearing impairment and olfactory dysfunction in ET patients were identified. The prevalence of hearing impairment is higher in ET patients than healthy controls or Parkinson disease. Cochlear pathologies are suggested as the underlying cause, but there is still a lack of information about retrocochlear pathologies and central auditory processing. Reports on olfactory dysfunction have conflicting results. The presence of mild olfactory dysfunction in ET was suggested. Conflicting results may be due to the lack of consideration of the disease's heterogeneity, but according to recent data, most studies do not find prominent evidence of olfactory loss in ET. Conclusion: Although there is increasing interest in studies on non-motor symptoms in ET, there are few studies on sensory deficits, which are of particularly high prevalence. More studies are needed on to investigate the basis of non-motor symptoms, including sensory deficits.

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Audio-vestibular evaluation in patients with essential tremor

Cited by 13 publications

References 16 publications

Non-motor symptoms in essential tremor: A review of the current data and state of the field

Non-motor symptoms in essential tremor: A review of the current data and state of the field

Essential tremor: diagnosis and management

Auditory and Olfactory Deficits in Essential Tremor – Review of the Current Evidence

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