Audio-Vocal Interaction in Single Neurons of the Monkey Ventrolateral Prefrontal Cortex

Hage, Steffen R.; Nieder, Andreas

doi:10.1523/jneurosci.2371-14.2015

Cited by 58 publications

(32 citation statements)

References 64 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recently, it has been shown that monkeys are able to show vocal usage learning in a well-controlled experimental design53 and that prefrontal and premotor structures might serve as potential hubs controlling such complex audio-vocal communicative behaviours5859606162. It would be interesting to see whether and how such frontal cortex circuits contribute to priming of vocal behaviour in response to social experience.…”

Section: Discussionmentioning

confidence: 99%

Limiting parental feedback disrupts vocal development in marmoset monkeys

2017

View full text Add to dashboard Cite

Vocalizations of human infants undergo dramatic changes across the first year by becoming increasingly mature and speech-like. Human vocal development is partially dependent on learning by imitation through social feedback between infants and caregivers. Recent studies revealed similar developmental processes being influenced by parental feedback in marmoset monkeys for apparently innate vocalizations. Marmosets produce infant-specific vocalizations that disappear after the first postnatal months. However, it is yet unclear whether parental feedback is an obligate requirement for proper vocal development. Using quantitative measures to compare call parameters and vocal sequence structure we show that, in contrast to normally raised marmosets, marmosets that were separated from parents after the third postnatal month still produced infant-specific vocal behaviour at subadult stages. These findings suggest a significant role of social feedback on primate vocal development until the subadult stages and further show that marmoset monkeys are a compelling model system for early human vocal development.

show abstract

Section: Discussionmentioning

confidence: 99%

Limiting parental feedback disrupts vocal development in marmoset monkeys

2017

View full text Add to dashboard Cite

show abstract

“…Previous single-unit (Hage and Nieder 2015; Hwang and Romanski 2015; Romanski et al, 2005; Sugihara et al, 2006) and neuroimaging results (Grady et al, 2008; Rama et al, 2004; Rama and Courtney 2005; Strand et al, 2008; Zatorre et al, 1994) have suggested that ventral PFC is important for auditory processing and auditory working memory. The inactivation experiments in Plakke et al, (2015) provides direct evidence that VLPFC is an essential region for auditory working memory and suggests VLPFC is a major end point of the auditory ventral stream, necessary for auditory cognition.…”

Section: Vlpfc Is Essential For Auditory Working Memory and Audiovisumentioning

confidence: 96%

Neural circuits in auditory and audiovisual memory

Plakke

Romanski

2016

Brain Research

View full text Add to dashboard Cite

Working memory is the ability to employ recently seen or heard stimuli and apply them to changing cognitive context. Although much is known about language processing and visual working memory, the neurobiological basis of auditory working memory is less clear. Historically, part of the problem has been the difficulty in obtaining a robust animal model to study auditory short-term memory. In recent years there has been neurophysiological and lesion studies indicating a cortical network involving both temporal and frontal cortices. Studies specifically targeting the role of the prefrontal cortex (PFC) in auditory working memory have suggested that dorsal and ventral prefrontal regions perform different roles during the processing of auditory mnemonic information, with the dorsolateral PFC performing similar functions for both auditory and visual working memory. In contrast, the ventrolateral PFC (VLPFC), which contains cells that respond robustly to auditory stimuli and that process both face and vocal stimuli may be an essential locus for both auditory and audiovisual working memory. These findings suggest a critical role for the VLPFC in the processing, integrating, and retaining of communication information.

show abstract

“…This stream primarily encodes auditory space. Converging auditory input in the ventro-lateral PFC (vlPFC) gives rise to neurons that respond to the spatial and nonspatial attributes of complex auditory stimuli (Cohen et al, 2004), and represent complex acoustic stimuli such as species-specific vocalizations (Romanski and Goldman-Rakic, 2002; Averbeck and Romanski, 2006; Hage and Nieder, 2015) and sound categories (Russ et al, 2007; Lee et al, 2009). …”

Section: Multisensory Innervation Of the Lateral Pfc And Premotor Arementioning

confidence: 99%

Magnitude Codes for Cross-Modal Working Memory in the Primate Frontal Association Cortex

Nieder

2017

Front. Neurosci.

View full text Add to dashboard Cite

Quantitative features of stimuli may be ordered along a magnitude continuum, or line. Magnitude refers to parameters of different types of stimulus properties. For instance, the frequency of a sound relates to sensory and continuous stimulus properties, whereas the number of items in a set is an abstract and discrete property. In addition, within a stimulus property, magnitudes need to be processed not only in one modality, but across multiple modalities. In the sensory domain, for example, magnitude applies to both to the frequency of auditory sounds and tactile vibrations. Similarly, both the number of visual items and acoustic events constitute numerical quantity, or numerosity. To support goal-directed behavior and executive functions across time, magnitudes need to be held in working memory, the ability to briefly retain and manipulate information in mind. How different types of magnitudes across multiple modalities are represented in working memory by single neurons has only recently been explored in primates. These studies show that neurons in the frontal lobe can encode the same magnitude type across sensory modalities. However, while multimodal sensory magnitude in relative comparison tasks is represented by monotonically increasing or decreasing response functions (“summation code”), multimodal numerical quantity in absolute matching tasks is encoded by neurons tuned to preferred numerosities (“labeled-line code”). These findings indicate that most likely there is not a single type of cross-modal working-memory code for magnitudes, but rather a flexible code that depends on the stimulus dimension as well as on the task requirements.

show abstract

Audio-Vocal Interaction in Single Neurons of the Monkey Ventrolateral Prefrontal Cortex

Cited by 58 publications

References 64 publications

Limiting parental feedback disrupts vocal development in marmoset monkeys

Limiting parental feedback disrupts vocal development in marmoset monkeys

Neural circuits in auditory and audiovisual memory

Magnitude Codes for Cross-Modal Working Memory in the Primate Frontal Association Cortex

Contact Info

Product

Resources

About