2023
DOI: 10.3389/fneur.2023.1223074
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Audiogenic epileptic DBA/2 mice strain as a model of genetic reflex seizures and SUDEP

Francesca Bosco,
Lorenza Guarnieri,
Antonio Leo
et al.

Abstract: Epilepsy is a chronic neurological disease characterized by abnormal brain activity, which results in repeated spontaneous seizures. Sudden unexpected death in epilepsy (SUDEP) is the leading cause of seizure-related premature death, particularly in drug-resistant epilepsy patients. The etiology of SUDEP is a structural injury to the brain that is not fully understood, but it is frequently associated with poorly controlled and repeated generalized tonic–clonic seizures (GTCSs) that cause cardiorespiratory and … Show more

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