Audiological follow-up of children with congenital Zika syndrome

Abstract

How does the auditory function of children with congenital Zika syndrome present during the first three years of life? To determine the auditory function of children with congenital Zika syndrome during the first three years of life and estimate the frequency and long-term presentation of hearing loss in this syndrome, an auditory assessment with screening and diagnostic tests was conducted. The screening test consisted of measuring the short latency ABR using click stimuli. If the ABR click indicated hearing loss, confirmation was obtained with a frequency-specific ABR (FS-ABR), in which the stimuli were tone bursts at frequencies of 500 and 2000 Hz by bone and air conduction. This case series included 107 children with confirmed congenital Zika syndrome, and the cumulative incidence of sensorineural hearing loss in the first three years of life was 9.3% (10/107). There were no cases of delayed-onset or progressive deficits in hearing. Early presentation of sensorineural hearing loss seems to occur with a higher frequency in children with congenital Zika syndrome than in the general population. Sensorineural hearing loss resulting from congenital Zika virus infection does not appear to present with delayed onset or with progressive deficits.

Evaluation of the maturational auditory process in children with the infection by Zika congenital syndrome

“…there was no presence of progressive hearing loss in the sample members up to five years of age. A national study 37 assessed 107 children up to three years of age with ZIKV infection and also found no progressive hearing loss in the sample.…”

“…Audiological tests have shown cochlear disorders. brainstem synchrony within the normal range and alterations in tests that assess essential cortical functions for language development [37][38][39] . A study that assessed 88 children infected by ZIKV with normal hearing thresholds found delayed development of communication skills in 87.5% of the sample.…”

Avaliação do processo maturacional auditivo em crianças portadoras da síndrome da infecção congênita pelo Zika vírus

“…Testes audiológicos tem mostrado alterações cocleares. sincronia de tronco encefálico dentro da normalidade e alterações em testes que avaliam funções corticais essenciais para o desenvolvimento de linguagem [37][38][39] . Estudo que avaliou 88 crianças infectadas pelo ZIKV com limiares auditivos normais.…”

Encoding of speech sounds with frequency-following response in infants with Congenital Zika Syndrome: A case-controlled study

“…Studies of hearing acuity point to the presence of both peripheral hearing disorders [5][6][7][8][9][10] or normal hearing 11 . Other authors 12 point out that in patients with CZV, sensorineural hearing loss can be considered a clinical feature. And that the hearing loss seems to be present at birth and no change or worsening of the auditory condition has been observed.…”