Auditing hospital drug utilisation by means of defined daily doses per bed-day a methodological study

Bergman, Ulf; Christenson, I; Jansson, Bengt; Wiholm, Bengt‐Erik

doi:10.1007/bf00561898

Cited by 39 publications

(20 citation statements)

References 9 publications

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“…Drug utilization research studies conducted in the inpatient settings are effective tools that help in evaluating the drug prescribing trends, efficiency, and cost-effectiveness of hospital formularies. There is always a variation in drug utilization among different countries and even among health institutions within a country and sometimes within the same institute at different point of time probably because of changing disease trends over a period of time [2]. Conducting periodic studies of pattern of drug use in various hospital settings or patient populations is therefore essential to critically analyse the current hospital drug policies and to make recommendations based on various guidelines to improve upon the current drug usage pattern in the future, if needed.…”

Section: Introductionmentioning

confidence: 99%

Drug Utilization Study in Medical Emergency Unit of a Tertiary Care Hospital in North India

Kaur

Rajagopalan

Kaur

et al. 2014

Emergency Medicine International

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Objective. To generate data on the drug utilization pattern and cost of drug treatment and to determine the rationality of prescriptions. Methods. A retrospective cross-sectional drug utilization study was conducted in the medical emergency unit of our hospital. Patient case records were reviewed to extract data on the pattern of drug use. Cost of drug treatment for the emergency visit was calculated by referring to the cost mentioned in Monthly Index of Medical Specialties and the rationality of prescriptions was evaluated using WHO core indicators of drug utilization. Results. 1100 case records were reviewed. Majority of patients received proton pump inhibitors followed by multivitamins. The median cost per prescription was 119.23$ (7.32$–7663.46$). Majority (49.9%) of drug cost was driven by antibiotics alone. An average of 4.9 drugs was prescribed per prescription. There were 14.89% encounters with antibiotics. 75.17% of the drugs were given as injectables and only 29.27% of the drugs were prescribed as generics. Conclusion. There is need to rationalize the drug therapy in terms of increasing prescribing of drugs by generic name and to avoid overuse of PPIs and multivitamins in emergency unit. Also the hospital pharmacy should be encouraged to procure more cost effective alternative antibiotics in future.

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Section: Introductionmentioning

confidence: 99%

Drug Utilization Study in Medical Emergency Unit of a Tertiary Care Hospital in North India

Kaur

Rajagopalan

Kaur

et al. 2014

Emergency Medicine International

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“…[5][6][7][8][10][11][12][13][14][15] Occorre sottolineare con grande evidenza come la DDD sia un'unità tecnica di misura e di confronto, alla quale non si può, né si deve, attribuire il significato di dose media prescritta od utilizzata e tanto meno di dose raccomandata.…”

Section: Defined Daily Doses (Ddd) E Prescribed Daily Doses (Pdd)unclassified

Unita di consumo dei farmaci e valutazioni farmacoeconomiche: uso e misuso di DDD e PDD

Eandi¹

2002

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INTRODUZIONELe valutazioni farmacoeconomiche possono avere finalità differenti e possono utilizzare tecniche diverse in funzione degli obiettivi specifici del decisore.Talora la finalità è quella di analizzare l'andamento della spesa farmaceutica a diversi livelli di aggregazione del sistema sanitario (nazionale, regionale, aziendale, ospedaliera) o per gruppi terapeutici o per singoli farmaci. In questo caso una semplice analisi dei costi d'acquisto dei farmaci prescritti, dispensati o realmente consumati può essere adeguata per soddisfare le istanze del decisore. La rilevazione dei farmaci prescritti, dispensati o consumati può essere attuata con varie tecniche epidemiologiche, estraendo informazioni a vari livelli della catena distributiva; solo in casi particolari si ottengono dati di utilizzo estraendoli direttamente dalla storia clinica del singolo paziente: generalmente questo avviene nel corso di studi clinici tarati su obiettivi specifici e limitati a singoli farmaci o a gruppi di farmaci omogenei.In ogni caso, la quantificazione dei consumi o dell'utilizzazione dei farmaci deve essere attuata mediante unità di misura che permettano un confronto tra serie di dati trasversali (ad esempio, confronto tra nazioni, regioni, ASL, divisioni ospedaliere) e longitudinali (ad esempio, confronto tra anni successivi). Le tecniche più frequentemente utilizzate per analizzare e confrontare il consumo dei farmaci sono basate su alcuni indicatori costruiti attorno al sistema di unità di misure, denominato Defined Daily Doses (DDD), o attorno al parametro statistico, conosciuto come Prescribed Daily Doses (PDD).Unita di consumo dei farmaci e valutazioni farmacoeconomiche: uso e misuso di DDD e PDD Mario Eandi* ABSTRACTIn pharmacoeconomical evaluations the quantification of drug utilization has to be done on the basis of measurement units that allow comparisons among series of longitudinal and transversal data. The most common techniques used for the analysis and the comparison of drug utilization patterns are based either on the Defined Daily Dose (DDD), a unit system proposed by WHO's Drug Utilization Research Group, or on the Prescribed Daily Dose (PDD), a statistical parameter obtained from the analysis of drug prescriptions. This article illustrates the meaning of the main indicators of drug consumption that can be build with these techniques, underlining their utility and limitations. The DDD is the conventionally established theoretical mean daily dose of a drug, referred to a way of administration and to its main indication. It is, therefore, a mere technical measurement unit that cannot be interpreted as mean prescribed or consumed dose, and even less as recommended dose. The PDD, on the contrary, is not a measurement unit but a statistical mean value, that expresses the central tendency of the prescription variability in a defined setting. Starting from Italian data on the consumption of wide-spread antibiotics, the use and interpretation of various indicators based on the DDDs and PDDs are discussed. The param...

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“…[8] Drug utilization pattern varies from countries to countries and even among hospital within the same country and sometime within the same hospital at different point of time possibly because of changing disease trends over a period of time. [7,9] Pattern of drug utilization is studied to estimate the incidence and prevalence of drug use, to analyze that the recommended guidelines for prescription are being followed or not. [2] To compare, analyze and present statistical data of drug utilization research, the anatomical and therapeutic chemical (ATC) classification systems is accepted worldwide and recommended by WHO.…”

Section: Introductionmentioning

confidence: 99%

Drug Utilization Patterns in the Emergency Department of Najran University Hospital, Najran

Alkahtani¹

2018

JPPCM

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Auditing hospital drug utilisation by means of defined daily doses per bed-day a methodological study

Cited by 39 publications

References 9 publications

Drug Utilization Study in Medical Emergency Unit of a Tertiary Care Hospital in North India

Drug Utilization Study in Medical Emergency Unit of a Tertiary Care Hospital in North India

Unita di consumo dei farmaci e valutazioni farmacoeconomiche: uso e misuso di DDD e PDD

Drug Utilization Patterns in the Emergency Department of Najran University Hospital, Najran

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