Auditory evoked potentials in children and adolescents with Down syndrome

Abstract

Down syndrome, or trisomy 21, is the most common genetic alteration in humans. The syndrome presents with several features, including hearing loss and changes in the central nervous system, which may affect language development in children and lead to school difficulties. The present study aimed to investigate group differences in the central auditory system by long-latency auditory evoked potentials and cognitivepotential. An assessment of 23 children and adolescents with Down syndrome was performed, and a control group composed of 43 children and adolescents without genetic and/or neurological changes was used for comparison. All children underwent evaluation with pure tone and vocal audiometry, acoustic immitance measures, longlatency auditory evoked potentials, and cognitive potential. Longer latencies of the waves were found in the Down syndrome group than the control group, without significant differences in amplitude, suggesting that individuals with Down syndrome have difficulty in discrimination and auditory memory. It is, therefore, important to stimulate and monitor these children in order to enable adequate development and improve their life quality. We also emphasize the importance of the application of auditory evoked potentials in clinical practice, in order to contribute to the early diagnosis of hearing alterations and the development of more research in this area.central auditory evaluation, Down syndrome, electrophysiology, event-related potentials, evoked potentials, hearing, trisomy 21

Achados audiológicos na síndrome de Rubinstein-Taybi: revisão sistemática

“…As medidas eletrofisiológicas são amplamente empregadas para diagnósticos funcionais [24] e podem ser registrados em diferentes porções da via auditiva [25,26]. Ademais, são importantes na avaliação de crianças que não conseguem responder a exames subjetivos e comportamentais [27].…”

İşitme kaybı olan down sendromlu çocuk hastada eşlik eden otistik bulgular

“…(Ji, Capone, & Kaufmann, 2011). Bununla beraber çeşitli araştırmalarda DS'li çocukların yaşamının ilk yılında %34-38 oranında iletim tipi işitme kaybı (İTİK), %6 oranında sensörinöral işitme kaybı ve %3 oranında mikst tip işitme kaybı görülebildiği bildirilmektedir (Asim et al, 2015;Bernardi et al, 2017;Gregory et al, 2018;Hunter et al, 2017;Kreicher et al, 2018). Bu nedenle DS'li çocukların işitmesinin değerlendirmesi ve düzenli takibi önemlidir.…”

“…Ayrıca anatomik yapılardaki bazı farklılıklar nedeniyle işitme kaybına yatkındırlar. DS'li çocuklarda sıklıkla iletim tipi işitme kaybı meydana gelse de, sensörinöral veya mikst tip işitme kaybı da görülebilmektedir (Asim, Kumar, Muthuswamy, Jain, & Agarwal, 2015;Bernardi, Pires, Oliveira, & Nisihara, 2017;Gregory, Rosa, Zen, & Sleifer, 2018;Hunter et al, 2017;Kreicher, Weir, Nguyen, & Meyer, 2018).…”

Диагностика И Коррекция Слухового Восприятия У Детей 8–10-Летнего Возраста С Умственной Отсталостью

“…КОРРЕКЦИОННАЯ ПСИХОЛОГИЯ наличие более длительных латентных периодов основных пиков при отсутствии существенных различий в амплитуде (Gregory et al, 2018). При синдроме Вильямса также обнаружено наличие более длительной латентности, а также сниженной амплитуды компонентов P1, N1, N2 и P3 (Fagundes Silva et al, 2021).…”