Auditory evoked response to an oddball paradigm in children wearing cochlear implants

Deroche, Mickael L. D.; Wolfe, Jace; Neumann, Sara; Manning, Jacy; Towler, William; Alemi, Razieh; Bien, Alexander G.; Koirala, Nabin; Hanna, Lindsay; Henry, Lauren; Gracco, Vincent L.

doi:10.1016/j.clinph.2023.02.179

Cited by 8 publications

(5 citation statements)

References 100 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 26 Here, we found group differences and correlations with individual outcomes, so we strongly suspect some of this variability to originate from cross-modal reorganization. Recent explorations of auditory cortex response to an oddball paradigm 56 and resting-state networks 58 in the same sample of children also revealed striking group differences and links to language and literacy outcomes, reinforcing the notion that this neuroimaging approach to CI outcomes is promising and has clinical relevance.…”

Section: Discussionmentioning

confidence: 76%

“…The data from the two imaging techniques were acquired sequentially, with counterbalanced order. Several other tasks were conducted using the same techniques in each child on the same day: a low-level auditory task, 56 a motor task, 54 a phonological task (spoken/written words and pseudo-words), an audiovisual integration task, 57 emotional processing (a 10-min child-friendly video from the movie ‘Despicable Me’) and a 7-min resting-state recording. 58 As the entire protocol for each technique was substantial, they were conducted at different times with a large break in between.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Cross-modal plasticity in children with cochlear implant: converging evidence from EEG and functional near-infrared spectroscopy

Deroche,

Wolfe,

Neumann

et al. 2024

Brain Communications

View full text Add to dashboard Cite

Over the first years of life, the brain undergoes substantial organization in response to environmental stimulation. In a silent world, it may promote vision by 1) recruiting resources from the auditory cortex and 2) making the visual cortex more efficient. It is unclear when such changes occur and how adaptive they are, questions that children with cochlear implants can help address. Here, we examined 7 to 18 years old children: 50 had cochlear implants, with delayed or age-appropriate language abilities, and 25 had typical hearing and language. High-density electroencephalography and functional near-infrared spectroscopy were used to evaluate cortical responses to a low-level visual task. Evidence for a weaker visual cortex response and less synchronized or less inhibitory activity of auditory association areas in the implanted children with language delays suggests that cross-modal reorganization can be maladaptive and does not necessarily strengthen the dominant visual sense.

show abstract

Section: Discussionmentioning

confidence: 76%

Section: Methodsmentioning

confidence: 99%

Cross-modal plasticity in children with cochlear implant: converging evidence from EEG and functional near-infrared spectroscopy

Deroche,

Wolfe,

Neumann

et al. 2024

Brain Communications

View full text Add to dashboard Cite

show abstract

“…It has been clearly established that congenital sensorineural hearing loss has an impact on neural structure and function in children ( Campbell and Sharma, 2016 ; Xia et al, 2017 ; Calcus et al, 2019 ; Wang et al, 2019 ; Simon et al, 2020 ; Bonna et al, 2021 ; Deroche et al, 2023 ). In the present study, changes in neural organization and how they are related to subsequent development of language and reading provide insight into the neural adaptation after cochlear implantation.…”

Section: Discussionmentioning

confidence: 99%

Dynamic networks differentiate the language ability of children with cochlear implants

Koirala,

Deroche,

Wolfe

et al. 2023

Front. Neurosci.

Self Cite

View full text Add to dashboard Cite

BackgroundCochlear implantation (CI) in prelingually deafened children has been shown to be an effective intervention for developing language and reading skill. However, there is a substantial proportion of the children receiving CI who struggle with language and reading. The current study–one of the first to implement electrical source imaging in CI population was designed to identify the neural underpinnings in two groups of CI children with good and poor language and reading skill.MethodsData using high density electroencephalography (EEG) under a resting state condition was obtained from 75 children, 50 with CIs having good (HL) or poor language skills (LL) and 25 normal hearing (NH) children. We identified coherent sources using dynamic imaging of coherent sources (DICS) and their effective connectivity computing time-frequency causality estimation based on temporal partial directed coherence (TPDC) in the two CI groups compared to a cohort of age and gender matched NH children.FindingsSources with higher coherence amplitude were observed in three frequency bands (alpha, beta and gamma) for the CI groups when compared to normal hearing children. The two groups of CI children with good (HL) and poor (LL) language ability exhibited not only different cortical and subcortical source profiles but also distinct effective connectivity between them. Additionally, a support vector machine (SVM) algorithm using these sources and their connectivity patterns for each CI group across the three frequency bands was able to predict the language and reading scores with high accuracy.InterpretationIncreased coherence in the CI groups suggest overall that the oscillatory activity in some brain areas become more strongly coupled compared to the NH group. Moreover, the different sources and their connectivity patterns and their association to language and reading skill in both groups, suggest a compensatory adaptation that either facilitated or impeded language and reading development. The neural differences in the two groups of CI children may reflect potential biomarkers for predicting outcome success in CI children.

show abstract

“…Along with other reports on the same pediatric population ( Deroche et al, 2023 ; Koirala et al, 2023 ; Wolfe et al, 2021 ), we explored motor cortex activity and its association with visual and auditory networks in children with CIs. We found an increase in HbO and a decrease in HbR in the motor cortex of all participants, irrespective of their hearing and language status.…”

Section: Discussionmentioning

confidence: 99%

Motor Processing in Children With Cochlear Implants as Assessed by Functional Near-Infrared Spectroscopy

Alemi,

Wolfe,

Neumann

et al. 2023

Percept Mot Skills

Self Cite

View full text Add to dashboard Cite

Auditory-motor and visual-motor networks are often coupled in daily activities, such as when listening to music and dancing; but these networks are known to be highly malleable as a function of sensory input. Thus, congenital deafness may modify neural activities within the connections between the motor, auditory, and visual cortices. Here, we investigated whether the cortical responses of children with cochlear implants (CI) to a simple and repetitive motor task would differ from that of children with typical hearing (TH) and we sought to understand whether this response related to their language development. Participants were 75 school-aged children, including 50 with CI (with varying language abilities) and 25 controls with TH. We used functional near-infrared spectroscopy (fNIRS) to record cortical responses over the whole brain, as children squeezed the back triggers of a joystick that vibrated or not with the squeeze. Motor cortex activity was reflected by an increase in oxygenated hemoglobin concentration (HbO) and a decrease in deoxygenated hemoglobin concentration (HbR) in all children, irrespective of their hearing status. Unexpectedly, the visual cortex (supposedly an irrelevant region) was deactivated in this task, particularly for children with CI who had good language skills when compared to those with CI who had language delays. Presence or absence of vibrotactile feedback made no difference in cortical activation. These findings support the potential of fNIRS to examine cognitive functions related to language in children with CI.

show abstract

Auditory evoked response to an oddball paradigm in children wearing cochlear implants

Cited by 8 publications

References 100 publications

Cross-modal plasticity in children with cochlear implant: converging evidence from EEG and functional near-infrared spectroscopy

Cross-modal plasticity in children with cochlear implant: converging evidence from EEG and functional near-infrared spectroscopy

Dynamic networks differentiate the language ability of children with cochlear implants

Motor Processing in Children With Cochlear Implants as Assessed by Functional Near-Infrared Spectroscopy

Contact Info

Product

Resources

About