Auditory sensory memory as indicated by mismatch negativity in chronic alcoholism

Grau, Cai; Polo, M.D.; Yago, Elena; Gual, Antoni; Escera, Carles

doi:10.1016/s1388-2457(01)00490-4

Cited by 32 publications

(17 citation statements)

References 13 publications

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“…Therefore, in terms of automatic-controlled processing theory, the deficit in MMN observed in alcoholics could be interpreted as automatic dysfunction processing in contrast with the deficits in P300 that would reflect attentive (or effortful) information-processing impairment. However, not all studies found differences in ERP between alcoholic and control subjects [56,45,56]. Thus, while there is a strong link between alcohol abuse and symptoms of disinhibition, the MMN response does not offer any direct physiological evidence of this fact.…”

Section: Mismatch Negativity (Mmn)mentioning

confidence: 93%

Chronic alcoholism: Insights from neurophysiology

Campanella¹,

Petit²,

Maurage³

et al. 2009

Neurophysiologie Clinique/Clinical Neurophysiology

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SummaryIntroduction. -Increasing knowledge of the anatomical structures and cellular processes underlying psychiatric disorders may help bridge the gap between clinical signs and basic physiological processes. Accordingly, considerable insight has been gained in recent years into a common psychiatric condition, i.e., chronic alcoholism. Material and methods. -We reviewed various physiological parameters that are altered in chronic alcoholic patients compared to healthy individuals -continuous electroencephalogram, oculomotor measures, cognitive event-related potentials and event-related oscillations -to identify links between these physiological parameters, altered cognitive processes and specific clinical symptoms. Results. -Alcoholic patients display: (1) high beta and theta power in the resting electroencephalogram, suggesting hyperarousal of their central nervous system; (2) abnormalities in smooth pursuit eye movements, in saccadic inhibition during antisaccade tasks, and in prepulse inhibition, suggesting disturbed attention modulation and abnormal patterns of prefrontal activation that may stem from the same prefrontal ''inhibitory'' cortical dysfunction; (3) decreased amplitude for cognitive event-related potentials situated along the continuum of informationprocessing, suggesting that alcoholism is associated with neurophysiological deficits at the level of the sensory cortex and not only disturbances involving associative cortices and limbic structures; and (4) decreased theta, gamma and delta oscillations, suggesting cognitive disinhibition at a functional level. Discussion. -The heterogeneity of alcoholic disorders in terms of symptomatology, course and outcome is the result of various pathophysiological processes that physiological parameters * Corresponding author. E-mail address: salvatore.campanella@chu-brugmann.be (S. Campanella).

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Section: Mismatch Negativity (Mmn)mentioning

confidence: 93%

Chronic alcoholism: Insights from neurophysiology

Campanella¹,

Petit²,

Maurage³

et al. 2009

Neurophysiologie Clinique/Clinical Neurophysiology

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“…Researchers have reported a significantly greater attenuation of the MMN response for stimuli delivered at longer ISIs in specific clinical populations including the elderly (Gaeta et al 1992;Woods 1992;Pekkonen et al 1996), children with CATCH-22 syndrome learning problems (Kraus et al 1996;Cheour et al 1997), and those suffering from Parkinson's disease (Pekkonen et al 1994), Alzheimer's disease (Kazmerski et al 1997), chronic alcoholism (Ahveninen et al 2000;Grau et al 2001), and coma (Kane et al 1993). Since certain neural refractory functions are also known to vary with different forms of CNS dysfunction (Shagrass et al 1971;Alho et al 1994;Ornitz et al 1974;Papanicolaou et al 1984;Shucard et al 1984), it is possible that in some studies, the MMN response and neural refractory effects may temporally overlap.…”

Section: Mmn and Differential Waveform 3 An Evaluation Of The Mismatcmentioning

confidence: 99%

A Comparison of the mismatch negativity and a differential waveform response

Elangovan

Cranford

Walker

et al. 2005

International Journal of Audiology

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“…The lifetime of a memory trace in the sensory store has been reported to be reduced in patients with chronic alcoholism (Grau, Polo, Yago, Gual, & Escera, 2001;Zhang, Cohen, Porjesz, & Begleiter, 2001) and Alzheimer's disease (Engeland, Mahoney, Mohr, Ilivitsky, & Knott, 2002;Pekkonen, Jousmaki, Kononen, Reinikainen, & Partanen, 1994). The findings suggest that MMN can objectively identify sensory memory deficits in patients with memory impairments.…”

mentioning

confidence: 91%

Auditory sensory memory and language abilities in former late talkers: A mismatch negativity study

et al. 2010

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The present study investigated whether (a) a reduced duration of auditory sensory memory is found in late talking children and (b) whether deficits of sensory memory are linked to persistent difficulties in language acquisition. Former late talkers and children without delayed language development were examined at the age of 4 years and 7 months using mismatch negativity (MMN) with interstimulus intervals (ISIs) of 500 ms and 2000 ms. Additionally, short-term memory, language skills, and nonverbal intelligence were assessed. MMN mean amplitude was reduced for the ISI of 2000 ms in former late talking children both with and without persistent language deficits. In summary, our findings suggest that late talkers are characterized by a reduced duration of auditory sensory memory. However, deficits in auditory sensory memory are not sufficient for persistent language difficulties and may be compensated for by some children.

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Auditory sensory memory as indicated by mismatch negativity in chronic alcoholism

Cited by 32 publications

References 13 publications

Chronic alcoholism: Insights from neurophysiology

Chronic alcoholism: Insights from neurophysiology

A Comparison of the mismatch negativity and a differential waveform response

Auditory sensory memory and language abilities in former late talkers: A mismatch negativity study

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