Auditory threshold, phonologic demand, and incident dementia

Gallacher, John; Ilubaera, Victor; Ben-Shlomo, Yoav; Bayer, Antony James; Fish, Mark; Babisch, Wolfgang; Elwood, Peter Creighton

doi:10.1212/wnl.0b013e31826e263d

Cited by 213 publications

(263 citation statements)

References 34 publications

Supporting

Mentioning

242

Contrasting

Unclassified

Order By: Relevance

“…The previous studies of objective hearing loss used a pure tone audiometry test, whereas the current study used self‐reported hearing measures in the longitudinal analyses 6, 7, 11. Nevertheless, a significant positive association was found between the self‐reported and objective test measure in Wave 7.…”

Section: Discussioncontrasting

confidence: 59%

“…The current study built on previous longitudinal studies conducted in the United States and Wales that found that individuals with moderate and severe hearing loss were at greater risk of developing dementia 6, 7, 12, 22. Six hundred thirty‐nine adults aged 65 and older from the Baltimore Longitudinal Study of Aging were prospectively analysed over 11.9 years 7.…”

Section: Discussionmentioning

confidence: 99%

“…Older men from the Caerphilly Study in Wales (N = 1,057) were followed for 17 years, and an association was found between objective auditory threshold and dementia (OR = 2.67, 95% CI = 1.38–5.18). Unlike the other previous studies, they included only men in their analysis 6. Finally, the Cache County Study on Memory, Health, and Aging in the United States (N = 4,545) followed older adults (≥65) for 13 years and also found that hearing loss was an independent risk factor for developing dementia,12 although identification of hearing loss was questionable because it was based on interviewer ratings that were not a mandatory part of the assessment protocol.…”

Section: Discussionmentioning

confidence: 99%

“…There is also evidence that hearing loss could be a risk factor 6, 7, 8. As with dementia, the risk of hearing loss increases with age.…”

mentioning

confidence: 99%

See 3 more Smart Citations

Hearing Impairment and Incident Dementia: Findings from the English Longitudinal Study of Ageing

Davies

Cadar

Herbert

et al. 2017

J American Geriatrics Society

120

105

View full text Add to dashboard Cite

ObjectivesTo determine whether hearing loss is associated with incident physician‐diagnosed dementia in a representative sample.DesignRetrospective cohort study.SettingEnglish Longitudinal Study of Ageing.ParticipantsAdults aged 50 and older.MeasurementsCross‐sectional associations between self‐reported (n = 7,865) and objective hearing measures (n = 6,902) and dementia were examined using multinomial‐logistic regression. The longitudinal association between self‐reported hearing at Wave 2 (2004/05) and cumulative physician‐diagnosed dementia up to Wave 7 (2014/15) was modelled using Cox proportional hazards regression.ResultsAfter adjustment for potential confounders, in cross‐sectional analysis, participants who had self‐reported or objective moderate and poor hearing were more likely to have a dementia diagnosis than those with normal hearing (self‐reported: odds ratio OR = 1.6, 95% CI = 1.1–2.4 moderate hearing; OR = 2.6, 95% CI = 1.7–3.9 poor hearing, objective: OR = 1.6, 95% CI = 1.0–2.8 moderate hearing; OR = 4.4, 95% CI = 1.9–9.9 poor hearing). Longitudinally, the hazard of developing dementia was 1.4 (95% CI = 1.0–1.9) times as high in individuals who reported moderate hearing and 1.6 (95% CI = 1.1–2.0) times as high in those who reported poor hearing.ConclusionOlder adults with hearing loss are at greater risk of dementia than those with normal hearing. These findings are consistent with the rationale that correction of hearing loss could help delay the onset of dementia, or that hearing loss itself could serve as a risk indicator for cognitive decline.

show abstract

Section: Discussioncontrasting

confidence: 59%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…There is also evidence that hearing loss could be a risk factor 6, 7, 8. As with dementia, the risk of hearing loss increases with age.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Hearing Impairment and Incident Dementia: Findings from the English Longitudinal Study of Ageing

Davies

Cadar

Herbert

et al. 2017

J American Geriatrics Society

120

105

View full text Add to dashboard Cite

show abstract

“…1 Hearing loss in older adults impairs verbal communication, contributes to social isolation, 2 and has been independently associated with poorer cognitive functioning [3][4][5] and incident dementia. [6][7] While hearing aids improve audibility for most individuals with mild to moderate hearing loss, those who suffer from severe to profound hearing loss generally may acquire greater benefit from electrical hearing provided by a cochlear implant (CI). 8 Currently, the number of older adults in the United States who would potentially meet audiologic criteria for a CI is approximately 150,000, 1 but less than 5% of these older adults are likely to have received a CI System.…”

Section: Introductionmentioning

confidence: 99%

Long‐term Use of Cochlear Implants in Older Adults: Results from a Large Consecutive Case Series

Choi¹,

Contrera²,

Betz³

et al. 2014

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

INTRODUCTIONHearing loss is prevalent in one in three people over the age of 50, and two-thirds of those older than 70 years. 1 Hearing loss in older adults impairs verbal communication, contributes to social isolation, 2 and has been independently associated with poorer cognitive functioning [3][4][5] and incident dementia. [6][7] While hearing aids improve audibility for most individuals with mild to moderate hearing loss, those who suffer from severe to profound hearing loss generally may acquire greater benefit from electrical hearing provided by a cochlear implant (CI). 8 Currently, the number of older adults in the United States who would potentially meet audiologic criteria for a CI is approximately 150,000, 1 but less than 5% of these older adults are likely to have received a CI System. 9 Many factors could potentially account for the low rate of CI use in older adults, such as a general perception of hearing loss being an inconsequential part of aging and poor awareness of and access to cochlear implantation. Additionally, there are concerns about whether older adults could practically benefit from CI on a daily basis. Older adults can consistently acquire improved speech perception scores after CI in the clinical setting, 10 but patterns of CI use by older adults has received little review. Previous studies have reported results only in small cohorts of older adults with limited durations of follow-up. [11][12][13][14][15][16][17][18] The purpose of our study was to investigate long-term rates of CI use in a consecutive case series of older adults (≥60 years) who received their first CI from 1999-2011. MATERIALS AND METHODS STUDY COHORTWe queried the Johns Hopkins Listening Center database to retrieve all patients ≥ 60 years who received a first CI from 1999 to June 2011 (n = 447). The purpose of this study was to investigate rates of CI use in older adults which is generally defined by the United Nations as adults ≥ 60 years. 33 Of these patients, we were able to successfully obtain follow-up information from the patient or a proxy respondent for 397 individuals (89%) from June to August 2012, and these individuals comprise our analytic cohort. Characteristics of "responders" (n = 397) and "non-responders" (n = 50) did not differ significantly by age of implantation, onset of hearing loss, side of implantation, or manufacturer (data not shown). Non-responders were more likely to have been implanted earlier in the study time period than responders (p < .001). Of the 50 non-responders, 27 (54%) had died based on Social Security Death Index records. For these deceased non-responders, we were unable to obtain proxy information on their CI use at the time of death due to unavailable contact information for surviving family members. This study was approved by Johns Hopkins Institutional Review Board. DATA COLLECTION ON CI USEAs part of a quality assurance initiative at the Johns Hopkins Listening Center, we contacted all CI patients and their families to survey their daily CI use. Postal and email survey...

show abstract

The Safety and Efficacy of PF-04958242 in Age-Related Sensorineural Hearing Loss

Bednar

DeMartinis

Banerjee

et al. 2015

JAMA Otolaryngol Head Neck Surg

View full text Add to dashboard Cite

show abstract

Auditory threshold, phonologic demand, and incident dementia

Cited by 213 publications

References 34 publications

Hearing Impairment and Incident Dementia: Findings from the English Longitudinal Study of Ageing

Hearing Impairment and Incident Dementia: Findings from the English Longitudinal Study of Ageing

Long‐term Use of Cochlear Implants in Older Adults: Results from a Large Consecutive Case Series

The Safety and Efficacy of PF-04958242 in Age-Related Sensorineural Hearing Loss

Contact Info

Product

Resources

About