In an effort to delineate hydrologic conditions in Maine, the U.S. Geological Survey, in cooperation with the Maine Department of Transportation, used streamflow data to develop dependent variables for 130 regression equations for estimating monthly and annual mean and 1, 5, 10, 25, 50, 75, 90, 95, and 99 percentile streamflows for ungaged, unregulated rivers in Maine. Daily streamflow data from 24 rural unregulated basins with drainage areas between 14.9 and 1,419 square miles in Maine and northern New Hampshire were used in the derivation of the equations. Streamflow data collected from October 1, 1982, through September 30, 2012, were used to derive the dependent variables for this study to represent current [2015] hydrologic conditions in Maine and northern New Hampshire. Weighted least squares regression techniques were used to derive the final coefficients and measures of uncertainty for the regression equations. Eight basin characteristics serve as the explanatory variables: drainage area, distance from the coast, mean and maximum basin elevation, mean basin slope, mean basin percentage of hydrologic soil group A, fraction of sand and gravel aquifers, and percentage of open water. The largest average errors of prediction are associated with regression equations for the lowest streamflows derived for months during which the lowest streamflows of the year occur (such as the 5 and 1 monthly percentiles for August and September). The regression equations have been derived on the basis of streamflow and basin characteristics data for unregulated, rural drainage basins without substantial streamflow or drainage modifications (for example, diversions and (or) regulation by dams or reservoirs, tile drainage, irrigation, channelization, and impervious paved surfaces), therefore using the equations for regulated or urbanized basins with substantial streamflow or drainage modifications will yield results of unknown error. Input basin characteristics derived using techniques or datasets other than those documented in this report or using values outside the ranges used to develop these regression equations also will yield results of unknown error.