The objective of this research was to determine the specific difficulties that hospitalized students face in accessing inclusive education in hospital classrooms. The technique used is a documentary review; searches were conducted on Google Scholar, Dialnet, and Redalyc using keywords, and 18 documents were selected for thematic analysis. Four dimensions were identified that articulate the complexities of providing inclusive education in hospital classrooms; these are: Educational Barriers, Social and Emotional Aspects, Pedagogical Practices, and Interdisciplinary Collaboration; each contributed to a comprehensive understanding of the obstacles and opportunities to improve the education of hospitalized students, highlighting both the specific difficulties and the effective strategies in use to facilitate an adaptive and comprehensive educational environment. It is concluded that hospital classrooms are redefined as a wellness ecosystem, integrating education and health to fully support the student, proposing to transform education into an essential component of recovery and well-being, using therapeutic methodologies and continuous support networks to adapt learning to the medical and emotional needs of the hospitalized student.