Auricular Reconstruction Using Tissue-Engineered Alloplastic Implants for Improved Clinical Outcomes

Hwang, Chang Mo; Lee, Bu Kyu; Denethia, Green; Jeong, Seon Yeong; Khang, Gilson; Jackson, John D.; Atala, Anthony; Lee, Sang Jin; Yoo, James J.

doi:10.1097/01.prs.0000438460.68098.4b

Cited by 24 publications

(13 citation statements)

References 29 publications

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“…In the years since many research groups have published on the manufacture of structures from soft solids some of which allow for the incorporation of cells . Most recently, Hwang et al reported the production of a cartilage‐like structure for auricular reconstruction . Notably, the majority of additively manufactured soft‐solid structures exhibit relatively low complexity and are typically broader at their base than at their peak to reduce the risk of the structure collapsing.…”

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confidence: 99%

Suspended Manufacture of Biological Structures

et al. 2017

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Suspended Manufacture of Biological Structures

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“…There is a narrow gap between the scalp and ear cartilage. Therefore, it is necessary to widen the gap by augmentation of the mastoid where the ear diverges from scalp [ 4 ]. Currently, use of autologous costal cartilage is the standard treatment method.…”

Section: Discussionmentioning

confidence: 99%

Simple Aesthetic Correction for Patients with Acute Auriculocephalic Angle

Lee

Kang

Sun

2015

Arch Craniofac Surg

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BackgroundAcute auriculocephalic angle refers to an ear with helix that is spaced closely to the cranium. An increasing number of patients with acute auriculocephalic angle wish to undergo corrective operation for aesthetic purposes. However, there is a paucity of data regarding acute auriculocephalic angle. This paper proposes a treatment protocol for patients with acute auriculocephalic angle.MethodsWe performed a retrospective analysis of patients undergoing acute auriculocephalic angle (4 patients, 6 ears). Patient records were reviewed for demographic data as well as auricular measurements at preoperative, immediate postoperative and final follow-up evaluations.ResultsAll of the patients were men with a mean age of 36.5 years (range, 23-52 years). The mean follow-up period was 47.5 months (range, 28-60 months). Postoperative auriculocephalic angle was close to the normal auriculocephalic angle (25°-30°) without notable scars. Moreover, the patients had minimal contractions of the skin flaps without any hematoma or relapse.ConclusionWe propose the following three treatment protocols for patients with acute auriculocephalic angle: the posterior auricular muscle should be sufficiently released, the mastoid area should be augmented using implants, the skin should be repositioned with a superior auricular flap.

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“…These implants showed no evidence of skin necrosis, implant exposure, or extrusion compared with nonseeded controls after implantation into the dorsum of athymic mice. 68 One human study used injection implantation of cultured chondrocytes into the subcutaneous pocket on the fascia of the lower abdomen. Six months later, the neocartilage block was surgically harvested and carved into an auricle for implantation.…”

Section: Applications In Craniofacial Reconstruction and Plastic Surgerymentioning

confidence: 99%

Tissue Engineering for Otorhinolaryngology–Head and Neck Surgery

Lott

Janus

2014

Mayo Clinic Proceedings

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Tissue regeneration in otorhinolaryngology-head and neck surgery is a diverse area filled with specialized tissues and functions. Head and neck structures govern many of the 5 senses, swallowing, breathing, communication, facial animation, and aesthetics. Loss of these functions can have a severe negative effect on patient quality of life. Regenerative medicine techniques have the potential to restore these functions while minimizing the risks associated with traditional reconstruction techniques. This article serves as a review and update on some of the regenerative medicine research in this field. A description of the predominant clinical problems is presented, followed by a discussion of some of the most promising research working toward a solution. There are many noteworthy findings appropriate for inclusion, but limitations preclude mention of them all. This article focuses on laryngeal surgery, craniofacial reconstruction and plastic surgery, and otology and hearing.

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Auricular Reconstruction Using Tissue-Engineered Alloplastic Implants for Improved Clinical Outcomes

Cited by 24 publications

References 29 publications

Suspended Manufacture of Biological Structures

Suspended Manufacture of Biological Structures

Simple Aesthetic Correction for Patients with Acute Auriculocephalic Angle

Tissue Engineering for Otorhinolaryngology–Head and Neck Surgery

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