Australian baseline series allergens in assessment of allergic contact dermatitis in New South Wales

Cheng, Harriet; Konya, Joseph; Lobel, E.; Fernández‐Peñas, Pablo

doi:10.1111/ajd.13745

Cited by 1 publication

(2 citation statements)

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“…Studies conducted between 1993 and 2008 reported that the worldwide prevalence of contact sensitization caused by CAPB ranges from 1.4% to 9.8%, depending on the population studied 12 . Recent retrospective observational studies using local baseline series revealed that the patch test positivity rates of CAPB were 1.6% (89/5592 patients) in the North American Contact Dermatitis Group (NACDG) baseline series, 13 6.7% (50/748 patients) in the European baseline series 14 and 0.4% (4/972 patients) in the Australian baseline series 15 . In spite of the findings of these large studies, CAPB allergies have been attributed to the CAPB impurities DMAPA and AA.…”

Section: Discussionmentioning

confidence: 99%

“…12 Recent retrospective observational studies using local baseline series revealed that the patch test positivity rates of CAPB were 1.6% (89/5592 patients) in the North American Contact Dermatitis Group (NACDG) baseline series, 13 6.7% (50/748 patients) in the European baseline series 14 and 0.4% (4/972 patients) in the Australian baseline series. 15 In spite of the findings of these large studies, CAPB allergies have been attributed to the CAPB impurities DMAPA and AA. However, whether either impurity acts as a sensitizer, is still unclear.…”

Section: Concentrations Of Dmapa and Lapdma In The Raw Materials For ...mentioning

confidence: 99%

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Analysis of patch testing with cocamidopropyl betaine and its impurities in patients with intractable scalp dermatitis in a single clinic in Japan

Iijima,

Murayama,

Takayama

et al. 2023

Contact Dermatitis

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BackgroundThe allergen responsible for cocamidopropyl betaine (CAPB) allergies has been debated.ObjectivesTo investigate the sensitizing agents of CAPB, the patch test positivity rates of impurities were examined in Japanese patients with CAPB‐related allergic contact dermatitis.Materials and MethodsThirty patients with scalp dermatitis and positive patch tests for CAPB and/or lauramidopropyl betaine (LAPB) were enrolled in this study. They were patch tested with the detergents that they had been using at the time of their first visit and with the impurities dimethylaminopropylamine (DMAPA) and lauramidopropyl dimethylamine (LAPDMA).ResultsThe positivity rate in patch tests of the 37 detergents that the patients had been using was 78.4% (29/37). The positivity rates of DMAPA 1% pet., 1% aq. and 0.2% aq. were 32.1% (9/28), 14.3% (4/28) and 13.3% (4/30), respectively, whereas those of LAPDMA 0.1% and 0.05% were 30.0% (9/30) and 16.7% (5/30), respectively. Among the 30 patients, 6 exhibited positive results for both DMAPA and LAPDMA, 3 showed positive results for DMAPA alone and 6 produced positive results for LAPDMA alone.ConclusionPatch tests produced an overall positivity rate for DMAPA, LAPDMA or both of 50.0% (15/30) in patients with scalp dermatitis and positive patch test results for CAPB and/or LAPB.

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Section: Discussionmentioning

confidence: 99%

Section: Concentrations Of Dmapa and Lapdma In The Raw Materials For ...mentioning

confidence: 99%

Analysis of patch testing with cocamidopropyl betaine and its impurities in patients with intractable scalp dermatitis in a single clinic in Japan

Iijima,

Murayama,

Takayama

et al. 2023

Contact Dermatitis

View full text Add to dashboard Cite

show abstract

Australian baseline series allergens in assessment of allergic contact dermatitis in New South Wales

Cited by 1 publication

References 10 publications

Analysis of patch testing with cocamidopropyl betaine and its impurities in patients with intractable scalp dermatitis in a single clinic in Japan

Analysis of patch testing with cocamidopropyl betaine and its impurities in patients with intractable scalp dermatitis in a single clinic in Japan

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