Austrian Syndrome Caused by Highly Penicillin-Resistant Streptococcus pneumoniae

Muñóz, Patricia; Sainz, Juan José Gómez; Rodríguez‐Créixems, Marta; Santos, J. Solera; Alcalá, Luís; Bouza, Emilio

doi:10.1086/313542

Cited by 30 publications

(14 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Data are scarce regarding the treatment of pneumococcal endocarditis (PE) due to penicillin-resistant S. pneumoniae in adults [3,13,14], and the optimal therapy for this entity remains unknown [10,15,16]. Therefore, we analyzed the effect of penicillin resistance of S. pneumoniae on the presentation, outcome, and treatment of PE in a prospective multicenter study of infective endocarditis in adults in Spain.…”

Section: We Performed a Clinical Study Of Pneumococcal Endocarditis (mentioning

confidence: 99%

Effect of Penicillin Resistance ofStreptococcus pneumoniaeon the Presentation, Prognosis, and Treatment of Pneumococcal Endocarditis in Adults

et al. 2002

View full text Add to dashboard Cite

We performed a clinical study of pneumococcal endocarditis (PE) in adults at 15 major Spanish hospitals during a 21-year period (1978-1998). During this time, 63 patients had PE due to Streptococcus pneumoniae diagnosed. Of the 63 isolates recovered from these patients, 24 (38%) and 6 (10%) showed resistance to penicillin (minimum inhibitory concentration [MIC], 0.1-4 microg/mL) and cefotaxime (MIC, 1 microg/mL), respectively. Twenty-two (35%) of the patients died. Left-side heart failure, but not penicillin resistance, was independently associated with a higher risk of death (odds ratio, 1.33; 95% confidence interval, 1.04-1.71; P=.026). Patients without meningitis who had PE due to penicillin-resistant S. pneumoniae could be treated with high-dose penicillin or a third-generation cephalosporin if the MIC for penicillin was < or =1 microg/mL. For patients with concurrent meningitis, high doses of cefotaxime could be used if the MIC for cefotaxime was < or =1 microg/mL. Early recognition of heart failure and surgery may help to decrease mortality.

show abstract

Section: We Performed a Clinical Study Of Pneumococcal Endocarditis (mentioning

confidence: 99%

Effect of Penicillin Resistance ofStreptococcus pneumoniaeon the Presentation, Prognosis, and Treatment of Pneumococcal Endocarditis in Adults

et al. 2002

View full text Add to dashboard Cite

show abstract

“…Four cases of PRSP endocarditis have been reported in the English literature (table 1) [7][8][9][10]. In our review of the literature, 3 of the 5 cases had aortic valve involvement, and the remainder had mitral involvement.…”

mentioning

confidence: 75%

Penicillin-Resistant Streptococcus pneumoniae Endocarditis: A Case Report and Review

Siegel

Timpone

2001

Clinical Infectious Diseases

View full text Add to dashboard Cite

show abstract

“…The aortic valve was involved in 12 out of 16 patients and valve replacement was required in eight out of 12 patients. Other significant risk factors include sinus infection, immunosuppression, splenectomy and IV drug abuse [4,5].…”

Section: Case Reportmentioning

confidence: 99%

A Case of Austrian’s Triad in the ICU Complicated by Subarachnoid Hemorrhage

Kapoor¹,

Mandl²,

Thakkar³

et al. 2015

J Med Cases

View full text Add to dashboard Cite

show abstract

Austrian Syndrome Caused by Highly Penicillin-Resistant Streptococcus pneumoniae

Cited by 30 publications

References 2 publications

Effect of Penicillin Resistance ofStreptococcus pneumoniaeon the Presentation, Prognosis, and Treatment of Pneumococcal Endocarditis in Adults

Effect of Penicillin Resistance ofStreptococcus pneumoniaeon the Presentation, Prognosis, and Treatment of Pneumococcal Endocarditis in Adults

Penicillin-Resistant Streptococcus pneumoniae Endocarditis: A Case Report and Review

A Case of Austrian’s Triad in the ICU Complicated by Subarachnoid Hemorrhage

Contact Info

Product

Resources

About