Authenticity of vitamin D in modified vaginal health index in geriatric subjects

Bala, Ripan; Kaur, Harmanpreet; Nagpal, Madhu

doi:10.18203/2320-1770.ijrcog20164067

Cited by 4 publications

(16 citation statements)

References 2 publications

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“…In 6 studies, the inclusion and exclusion criteria and selective outcomes were clearly defined. The intervention and control groups were demonstrably comparable in 2 trials [21,23].…”

Section: The Potential Sources Of Biasmentioning

confidence: 94%

“…The importance of this review: Being free of sexual problems can improve the confidence and mental state of women [20]; therefore, it is important to resolve sexual problems associated with menopause. Accordingly, vitamin D may be useful in vaginal discomfort in menopause women [7,[21][22][23]; however, some experimental results are controversy [24,25].…”

Section: Effect Of Vitamin D On the Vaginal Health Of Menopausalmentioning

confidence: 99%

“…1 for the study flow diagram. Six trials were included in this review: 2 studies were individually randomized controlled trials (RCTs) [21,23] and 4 were quasirandomized [24,[26][27][28]. A total of 391 participants were part of the 6 trials.…”

Section: Description Of Studiesmentioning

confidence: 99%

“…Four trials did not report any attempt to blind assessors to treatment assignment [21,[26][27][28]. In 2 trial reports, the participants or providers, or both, were blinded to treatment allocation [23,24].…”

Section: Blinding (Performance Bias and Detection Bias)mentioning

confidence: 99%

“…Vitamin D alone versus placebo or no treatment Two studies used vitamin D alone vs. a placebo or no treatment. In the study of Rad et al [23], 1,000 IU doses of vitamin D vaginal suppository were used with for eight weeks, but in Bala et al [21]'s study 60,000 IU doses of vitamin D were administered orally and weekly. In two studies that included 244 menopausal women, both studies showed vitamin D was effective in the vaginal health of these women.…”

Section: Effects Of Interventionsmentioning

confidence: 99%

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Effect of Vitamin D on the Vaginal Health of Menopausal Women: A Systematic Review

et al. 2019

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Menopause is associated with the onset of climacteric symptoms due to low estradiol levels, which may cause insufficient maturation of the vaginal mucosa. Vitamin D may regulate the growth and differentiation of cells that are adversely affected due to low estradiol levels, thereby restoring vaginal health. The objective of this systematic review, the first on this subject, was to investigate the effect of vitamin D on the vaginal health of menopausal women. PubMed, Embase, Scopus, Web of Science, and Google Scholar databases and reference lists of hand-searched articles were searched for published studies from February 2000 to November 2018. The selection criteria were as follows: randomized or quasi-randomized trials that compared the effects of vitamin D or related compounds, alone or with calcium, on vaginal health (growth and differentiation of epithelial cells, dryness, acidity [pH]) outcomes in menopausal women. The methodological quality of these studies was examined using the Cochrane tool checklist by two independent investigators, following which the data were extracted. Of six examined studies, two showed that vitamin D administration improved the growth and differentiation of vaginal epithelial cells, improved vaginal pH, and decreased vaginal dryness in menopausal women. Although the level of evidence for the effects of vitamin D on vaginal health is low in our study, we concluded that vitamin D may improve the vaginal health of women, especially during menopause.

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“…In 6 studies, the inclusion and exclusion criteria and selective outcomes were clearly defined. The intervention and control groups were demonstrably comparable in 2 trials [21,23].…”

Section: The Potential Sources Of Biasmentioning

confidence: 94%

Section: Effect Of Vitamin D On the Vaginal Health Of Menopausalmentioning

confidence: 99%

Section: Description Of Studiesmentioning

confidence: 99%

Section: Blinding (Performance Bias and Detection Bias)mentioning

confidence: 99%

Section: Effects Of Interventionsmentioning

confidence: 99%

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Effect of Vitamin D on the Vaginal Health of Menopausal Women: A Systematic Review

et al. 2019

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Differences Between 25-hydroxyvitamin D Levels in Patients with Pelvic Organ Prolapse and Non-Pelvic Organ Prolapse: A Systematic Review

Kurniawati,

Rahmawati,

Widyasari

2023

Journal of Obstetrics and Gynaecology Canada

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Resolution of the national interdisciplinary council of experts "High-dose vitamin D (Devilam) in the practice of an obstetrician-gynecologist"

Andreeva,

Artymuk,

Vesnina

et al. 2024

Probl Endokrinol (Mosk)

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On March 28, 2024, the Council of Experts “High-dose vitamin D (Devilam) in the practice of obstetrician-gynecologist, gynecologist and endocrinologist” was held in Moscow with the participation of leading experts gynecologists, endocrinologists and obstetricians-gynecologists, during which new possibilities for the use of high-dose vitamin D in patients of various ages who need correction of existing vitamin D deficiency or insufficiency.

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Authenticity of vitamin D in modified vaginal health index in geriatric subjects

Cited by 4 publications

References 2 publications

Effect of Vitamin D on the Vaginal Health of Menopausal Women: A Systematic Review

Effect of Vitamin D on the Vaginal Health of Menopausal Women: A Systematic Review

Differences Between 25-hydroxyvitamin D Levels in Patients with Pelvic Organ Prolapse and Non-Pelvic Organ Prolapse: A Systematic Review

Resolution of the national interdisciplinary council of experts "High-dose vitamin D (Devilam) in the practice of an obstetrician-gynecologist"

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