Author Correction: Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

Abstract

In the version of this article initially published, the author affiliations incorrectly listed "Candiolo Cancer Institute FPO-IRCCS, Candiolo (TO), Italy" as "Candiolo Cancer Institute, Candiolo, Italy." The change has been made to the HTML and PDF versions of the article.

Virtual Colonoscopy: Clinical Advances and Practical Challenges

“…Colorectal cancer causes more than 700,000 annual deaths worldwide and it is estimated that approximately 145,000 new cases of CRC will be diagnosed in the United States in 2023. 2 In randomized trials, the relative risk of death from CRC was approximately 15% lower among persons who were assigned to undergo screening with stool-based testing. Similarly, in a pooled analysis of three randomized trials, the incidence of CRC was up to 25% lower after 10 to 12 years of follow-up among persons who had been invited to undergo CRC screening than among those who had not been invited.…”

“…Even though individuals with a personal or family history of colorectal neoplasia, in ammatory bowel disease, or hereditary forms of CRC are prone to developing polyps, 75-95% of all colon cancers develop in individuals with little or no genetic predisposition for malignancy. 2 Additionally, early-stage CRC is mostly asymptomatic, and many patients are diagnosed at advanced stages. 1,2 Moreover, it is well-known that if colorectal cancer is detected in early stage, it is curable.…”

“…2 Additionally, early-stage CRC is mostly asymptomatic, and many patients are diagnosed at advanced stages. 1,2 Moreover, it is well-known that if colorectal cancer is detected in early stage, it is curable. Therefore, early detection obviously reduces morbidity and mortality.…”