Author Correction: Sustainable drug release from polycaprolactone coated chitin-lignin gel fibrous scaffolds

Abdullah, Turdimuhammad; Gauthaman, Kalamegam; Mostafavi, Azadeh; Alshahrie, Ahmed; Salah, Numan; Morganti, Pierfrancesco; Chianese, Angelo; Tamayol, Ali; Memić, Adnan

doi:10.1038/s41598-022-19505-w

Cited by 3 publications

(3 citation statements)

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“…103 Nanofibers have long been regarded as important scaffolds due to their similar structure to the natural extracellular matrix, which aids in gas exchange and provides an optimal environment for improved cell adhesion, proliferation, and differentiation. 104,105 Template synthesis, drawing process, self-assembly, electrospinning, and phase separation are examples of nanofiber production methods. 106 Electrospun nanofibers, for example, are great platforms for wound dressings because they provide a moist environment and may be impregnated with various biological components to aid wound healing applications.…”

Section: Surface Nanotopographymentioning

confidence: 99%

Tuning foreign body response with tailor-engineered nanoscale surface modifications: fundamentals to clinical applications

Yadav¹,

Bachhuka²

2023

J. Mater. Chem. B

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Section: Surface Nanotopographymentioning

confidence: 99%

Tuning foreign body response with tailor-engineered nanoscale surface modifications: fundamentals to clinical applications

Yadav¹,

Bachhuka²

2023

J. Mater. Chem. B

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“…Electrospun non-woven scaffolds have useful properties for wound care applications and wound dressings [ 8 , 9 , 10 ] and can be easily functionalized for those purposes, e.g., to provide an optimally moist wound environment or deliver bioactive agents and active pharmaceutical ingredients (APIs) to drive the healing process. The fibrous microstructure of such scaffolds mimics the native extracellular matrix, allowing for selective mass transfer, such as gas exchange and the removal of wound exudates, thus providing an ideal microenvironment for cell adhesion, proliferation, and subsequent differentiation [ 11 ]. Also, electrospinning allows relatively easy incorporation of different drugs or growth factors into the dressing matrix, making it a promising drug delivery system [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Innovative Multilayer Electrospun Patches for the Slow Release of Natural Oily Extracts as Dressings to Boost Wound Healing

Fiaschini,

Carnevali,

Van der Esch

et al. 2024

Pharmaceutics

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Electrospinning is an advanced manufacturing strategy used to create innovative medical devices from continuous nanoscale fibers that is endowed with tunable biological, chemical, and physical properties. Innovative medical patches manufactured entirely by electrospinning are discussed in this paper, using a specific plant-derived formulation “1 Primary Wound Dressing©” (1-PWD) as an active pharmaceutical ingredient (API). 1-PWD is composed of neem oil (Azadirachta indica A. Juss.) and the oily extracts of Hypericum perforatum (L.) flowers, according to the formulation patented by the ENEA of proven therapeutic efficacy as wound dressings. The goal of this work is to encapsulate this API and demonstrate that its slow release from an engineered electrospun patch can increase the therapeutic efficacy for wound healing. The prototyped patch is a three-layer core–shell membrane, with a core made of fibers from a 1-PWD-PEO blend, enveloped within two external layers made of medical-grade polycaprolactone (PCL), ensuring mechanical strength and integrity during manipulation. The system was characterized via electron microscopy (SEM) and chemical and contact angle tests. The encapsulation, release, and efficacy of the API were confirmed by FTIR and LC-HRMS and were validated via in vitro toxicology and scratch assays.

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“…Chitin is the second largest natural polysaccharide in nature after cellulose, and chitin and its derivatives including chitosan and chitooligosaccharide have been shown to have outstanding application advantages in biomedicine, cosmetics, food industry and material science [1][2][3][4][5]. However, their exploitation is greatly limited by their insolubility in common reagents.…”

Section: Introductionmentioning

confidence: 99%

Streptomyces beihaiensis sp. nov., a chitin-degrading actinobacterium, isolated from shrimp pond soil

Xie

Zhang

et al. 2023

International Journal of Systematic and Evolutionary Microbiology

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A Gram-stain-positive actinobacterium, designated strain GXMU-J5T, was isolated from a sample of shrimp pond soil collected in Tieshangang Saltern, Beihai, PR China. The morphological, chemotaxonomic and phylogenetic characteristics were consistent with its classification in the genus Streptomyces . The organism formed an extensively branched substrate mycelium, with abundant aerial hyphae that differentiated into spores. Phylogenetic analysis of 16S rRNA gene sequences showed that strain GXMU-J5T was most related to Streptomyces kunmingensis DSM 41681T (similarity 97.74 %) and Streptomyces endophyticus YIM 65594T (similarity 96.80 %). However, the values of digital DNA–DNA hybridization, average nucleotide identity and evolutionary distance of multilocus sequence analysis between strain GXMU-J5T and its closest relatives indicated that it represented a distinct species. Strain GXMU-J5T contained ll-diaminopimelic acid and the major whole-cell hydrolysates were xylose and galactose. The predominant menaquinones of strain GXMU-J5T were revealed as MK-9(H4), MK-9(H6) and MK-9(H8). The polar lipids consisted of diphosphatidylglycerol, phosphatidylmethylethanolamine, phosphatidylethanolamine, phosphatidylglycerol, phosphatidylinositol mannosides and phospholipids of unknown structure containing glucosamine. The predominant cellular fatty acids were iso-C15 : 0, anteiso-C15 : 0, iso-C16 : 0, iso-C17 : 0 and anteiso-C17 : 0. The whole genome size of strain GXMU-J5T was 6.79 Mbp with a 71.39 mol% G+C content. Genomic analysis indicated that strain GXMU-J5T had the potential to degrade chitin. On the basis of these genotypic and phenotypic data, it is supported that strain GXMU-J5T represents a novel species of the genus Streptomyces , for which the name Streptomyces beihaiensis sp. nov. is proposed. The type strain is strain GXMU-J5T (=MCCC 1K08064T=JCM 35629T).

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Author Correction: Sustainable drug release from polycaprolactone coated chitin-lignin gel fibrous scaffolds

Cited by 3 publications

References 0 publications

Tuning foreign body response with tailor-engineered nanoscale surface modifications: fundamentals to clinical applications

Tuning foreign body response with tailor-engineered nanoscale surface modifications: fundamentals to clinical applications

Innovative Multilayer Electrospun Patches for the Slow Release of Natural Oily Extracts as Dressings to Boost Wound Healing

Streptomyces beihaiensis sp. nov., a chitin-degrading actinobacterium, isolated from shrimp pond soil

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