Autism spectrum disorder in Latin American families: Experiences in Chile.

Hartmann, Kathrin; Kozikowski, Christine; Urbano, Maria R.; Williams, Takeshia V.; Ba, Caroline Luong-Tran; Peterkin, Alexander L.

doi:10.1037/fsh0000340

Cited by 6 publications

(4 citation statements)

References 9 publications

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“…The generation of public policies on early detection is necessary for the timely identification of each child with ASD, and it is essential that the treatment of children begin at an early age to achieve a significant impact on their evolution. A study conducted in Chile by Hartmann et al showed associations between ASD traits, physician support, community engagement, stigma, and family stress, highlighting “the importance of future research to better understand and treat Latin American children with ASD and their families” [51]. This study was an exploratory study carried out by a non-invasive sampling of the oral mucosa, which is a multi-stratified flat epithelial tissue that originates in the ectoderm, as does the nervous system [24].…”

Section: Discussionmentioning

confidence: 99%

Alterations of Mitochondrial Biology in the Oral Mucosa of Chilean Children with Autism Spectrum Disorder (ASD)

Carrasco

Salazar

Tiznado

et al. 2019

Cells

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Autistic Spectrum Disorder (ASD) is characterized by the impairment of socio-communicative skills and the presence of restricted and stereotyped behavior patterns. Recent researches have revealed the influence of mitochondrial physiology on the development of ASD. Several research groups have identified defects in respiratory complexes, coenzyme-Q10 deficiency, increased oxidative damage, decreased of superoxide dismutase (SOD2). A study on the influence of mitochondrial physiology on the development of ASD can provide new alternatives and challenges. That is why we set ourselves the general objective to initiate studies of mitochondrial physiology in Chilean children with ASD. A sample of oral mucosa was collected in a group of 12 children diagnosed with ASD and 12 children without ASD. In children with ASD, we found a significant increase in mitochondrial DNA levels. Likewise, in these children, an increase in the protein oxidation was observed. Finally, a downward trend in the expression of the HIGD2A and SOD2 genes was observed, while DRP1, FIS1, MFN1, MFN2, and OPA1 gene expression show an upward trend. The increment of mitochondrial DNA, high oxidative stress, and high expression of the MFN2 gene could help as a scanner of the mitochondrial function in children with ASD.

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Section: Discussionmentioning

confidence: 99%

Alterations of Mitochondrial Biology in the Oral Mucosa of Chilean Children with Autism Spectrum Disorder (ASD)

Carrasco

Salazar

Tiznado

et al. 2019

Cells

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“…The third quantitative study was conducted in Chile and explored the relationship between the severity of symptoms in children with ASD and other family characteristics, including stigma (Hartmann et al, 2018). With a study-specific questionnaire, the authors found stigma to be positively associated with ASD overall traits, social impairment, language and communication deficits, and family stress but not related to restricted and repetitive behaviors (RRBs).…”

Section: Attitudes and Beliefs About Id Perceived By Families And Carmentioning

confidence: 99%

Stigma Toward Persons with Intellectual Disability in South America: A Narrative Review

Tenorio

Donoso

Ali

et al. 2020

Policy Practice Intel Disabi

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People with intellectual disability (ID) form one of the most underserved/stigmatized groups in society. Published data have documented stigma toward this population group in different countries. However, this phenomenon has received scant attention in South American countries. The aim of this work is to conduct a systematic search of published and gray literature in the area of stigma toward persons with ID within the 12 countries of the region to explore expression of stigma toward people with ID in the region. Systematic research of published data and gray literature, based on a previous published protocol, was run in this work. The search strategy included terms related to IDs being combined with stigma, prejudice, attitudes and stereotypes, and with the names of all the South American countries. Due to the known relationship between ID and Autism Spectrum Disorder, this term was included in the search. The search was conducted in English, Spanish, and Portuguese. A narrative approach to results is presented. Available information is organized by stakeholder groups, including persons with ID, families, caregivers, and mental health workers. The quality of the studies was analyzed based on the Mixed Method Appraisal Tool Version 2018, and results are variable. The results of the narrative review are indicative of the limited scientific study of stigma toward people with ID in South American countries and the clear sense that people with ID living in those countries report experience of stigmatizing attitudes. Future research, at population level, is needed in the region to ensure improvements in the quality of life and in the civil participation of people with ID.

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“…Backtranslation of Western instruments is one way that global mental health researchers have tried to assure accurate measurement, but many other issues need additional study. Hartmann et al (2018) use previous work on measurement of caregiver distress done in the United States to develop an instrument for a survey in Chile, a country that has a higher income than LMICs. Based on findings from Chile, the authors suggest that the caregiver instrument could be used in other countries in Latin America because of shared culture.…”

Section: Obstacles To Obtaining Mental Health Servicesmentioning

confidence: 99%

An introduction to global mental health.

Patterson¹,

Edwards²

2018

Families, Systems, & Health

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In general, readers of (FSH) practice in high income countries and in settings that have adequate resources. Providers can usually count on being able to offer the material resources and skills that patients need to heal. This bounty of resources is in contrast to many clinics in low- and middle-income countries (LMICs). The need for mental health services in LMICs is significant and growing because of upheaval caused by war and other disasters. The topics in this issue talk about the obstacles to obtaining mental health services, trends in global mental health, and FSH in the global mental health movement. (PsycINFO Database Record

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Autism spectrum disorder in Latin American families: Experiences in Chile.

Abstract: Results from this study highlight the importance of future research to better understand and treat Latin American children with ASD and their families. (PsycINFO Database Record

Cited by 6 publications

References 9 publications

Alterations of Mitochondrial Biology in the Oral Mucosa of Chilean Children with Autism Spectrum Disorder (ASD)

Alterations of Mitochondrial Biology in the Oral Mucosa of Chilean Children with Autism Spectrum Disorder (ASD)

Stigma Toward Persons with Intellectual Disability in South America: A Narrative Review

An introduction to global mental health.

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