Auto-Skin Transplantation in Dogs

Thannoon, Moyaser G.; Ibrahim, S. M.; Al-Badrany, M. S.

doi:10.33762/bvetr.2012.68922

Cited by 4 publications

(4 citation statements)

References 7 publications

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“…If blood vessels do not grow and develop well, donor skin will undergo necrosis [ 1 ]. Autograft and isograft can easily be conducted to animal [ 2 ]. Allograft and xenograft method of skin transplant have often been specifically described in small animal [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Changes in histopathology and cytokeratin AE1/AE3 expression in skin graft with different time on Indonesian local cats

et al. 2017

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Aim:A good skin graft histopathology is followed by formation of hair follicle, sweat gland, sebaceous gland, blood vessel, lightly dense connective tissue, epidermis, and dermis layer. This research aimed to observe histopathology feature and cytokeratin AE1/AE3 expression on cat skin post skin grafting within a different period of time.Materials and Methods:Nine male Indonesian local cats aged 1-2 years old weighing 3-4 kg were separated into three groups. First surgery created defect wound of 2 cm × 2 cm in size to whole groups. The wounds were left alone for several days, differing in interval between each group, respectively: Group I (for 2 days), Group II (for 4 days), and Group III (for 6 days). The second surgery was done to each group which harvested skin of thoracic area and applied it on recipient wound bed. On day 24th post skin graft was an examination of histopathology and cytokeratin AE1/AE3 immunohistochemistry.Results:Group I donor skin’s epidermis layer had not formed completely whereas epidermis of donor skin of Groups II and III had completely formed. In all group hair follicle, sweat gland, sebaceous gland, and neovascularization were found. The density of connective tissue in Group I was very solid than other groups. Cytokeratin AE1/AE3 expression was found on donor skin’s epithelial cell in epidermis and dermis layer with very brown intensity for Group II, brown intensity for Group II, and lightly brown for Group I.Conclusion:Histopathological structure and cytokeratin AE1/AE3 expression post skin graft are better in Groups II and III compared to Group I.

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Section: Introductionmentioning

confidence: 99%

Changes in histopathology and cytokeratin AE1/AE3 expression in skin graft with different time on Indonesian local cats

et al. 2017

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“…White blood cell number in the circulation will increase upon stimulation of myeloid tissue activity to produce more white blood cells into the circulation. The use of flunixine meglumine as non-steroid antiinflammation drug was in order to lower body immunity, so that on day 12 (group II) post transplantation donor skin could already be accepted by recipient (Erwin et al, 2016;Fowler 2006;Thannoon et al, 2012).…”

Section: Resultsmentioning

confidence: 99%

“…The transferred skin for transplant must be maintained with granulation source and vascularization. A solid planning with thoroughness, atraumatic surgery technique to minimize tension towards the wound, and bleeding test to measure the transferred skin's life viability need to be done (Nelissen and White, 2014;Thannoon et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Blood Profile of Domestic Cat (Felix catus) During Skin Graft Recovery with Different Period (PROFIL DARAH KUCING LOKAL SELAMA KESEMBUHAN AUTO-SKIN GRAFT DENGAN WAKTU YANG BERBEDA)

Erwin¹,

Gunanti²,

Handharyani³

et al. 2017

jveteriner

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Penelitian ini bertujuan melihat profil darah kucing lokal, meliputi sel darah merah, sel darah putih, hemoglobin, hematokrit, dan trombosit selama kesembuhan tranplantasi kulit secara autograft. Sebanyak sembilan ekor kucing lokal (Felix catus) jantan umur 1-2 tahun dengan bobot badan 3-4 kg dibagi menjadi tiga kelompok perlakuan. Pada kucing tersebut dilakukan pencukuran rambut dan disinfeksi di area kaki depan sisi lateral, selanjutnya dibuat luka sayat/incisi 2x2 cm. Luka dibalut dengan kasa steril yang dibasahi povidone iodine dan dibiarkan selama beberapa hari. Kucing dengan sayatan yang dibiarkan tersebut dikelompokan menjadi kelompok I (dua hari), kelompok II (empat hari) dan kelompok III (enam hari). Transplantasi dilakukan dengan mengambil kulit dari area thorak dan ditempatkan pada resipien dengan terlebih dahulu permukaan luka kulit donor dan dasar luka resipien dibersihkan dari jaringan subkutis. Pengambilan sampel darah dilakukan melalui vena cephalica antebrachii anterior pada hari ke-0, 3, 6, 9, 12, dan 18. Berdasarkan hasil penelitian terjadi perbedaan yang signifikan (P<0,05) terhadap jumlah sel darah merah, sel darah putih, hemoglobin, dan hematokrit, sedangkan jumlah trombosit tidak menunjukkan perbedaan yang signifikan (P>0,05) di antara kelompok perlakuan. Kondisi sistemik tubuh kucing kelompok II dan III lebih baik dibandingan kelompok I.

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“…In addition, immunosuppressive drugs are needed to minimize rejection [ 19 ]. The result of this research differs with the one on dogs, where autogenous transplantation can be applied on dogs with little rejection, in accordance with the animal’s own immunity [ 20 ].…”

Section: Discussionmentioning

confidence: 99%

Subjective and objective observation of skin graft recovery on Indonesian local cat with different periods of transplantation time

et al. 2016

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Aim:The success of a skin graft in a cat is highly dependent on the granulation formed by the base of recipient bed. Granulation by the base of recipient bed will form after several days after injury. This research aimed to observe subjective and objective profile of skin graft recovery on forelimb of cats with different periods of donor skin placement.Materials and Methods:Nine male Indonesian local cats aged 1-2 years old, weighing 3-4 kg were divided into three groups. The first surgery for creating defect wound of 2 cm×2 cm in size was performed in the whole group. The wound was left for several days with the respective interval for each group, respectively: Group I (for 2 days), Group II (for 4 days), and Group III (for 6 days). In the whole group, the second surgery was done by the harvesting skin of thoracic area which then applied on recipient bed of respective groups.Result:The donor skin on Group II was accepted faster compared to Group I and Group III. The donor skin did not show color differences compared to surrounding skin, painless, bright red in bleeding test had faster both hair growth and drug absorption. Test toward the size of donor skin and the effect of drugs did not show a significant difference between each group.Conclusion:The observe subjective and objective profile of skin graft recovery on forelimb of cats on Group II were accepted faster compared to Group I and III.

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Auto-Skin Transplantation in Dogs

Abstract: This study was conducted using auto-skin transplantation for repairing of large skin loss of one front limb in dogs. The study was carried out on 8 clinical cases of dogs that brought to the

Cited by 4 publications

References 7 publications

Changes in histopathology and cytokeratin AE1/AE3 expression in skin graft with different time on Indonesian local cats

Changes in histopathology and cytokeratin AE1/AE3 expression in skin graft with different time on Indonesian local cats

Blood Profile of Domestic Cat (Felix catus) During Skin Graft Recovery with Different Period (PROFIL DARAH KUCING LOKAL SELAMA KESEMBUHAN AUTO-SKIN GRAFT DENGAN WAKTU YANG BERBEDA)

Subjective and objective observation of skin graft recovery on Indonesian local cat with different periods of transplantation time

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