Background:The mallow is a perennial, herbaceous biennial plant of the Malvaceae family occupying an important place in the Algerian flora. Several investigations demonstrated that this plant is very rich in bioactive compounds and possesses a large plethora of therapeutic properties, making it an interesting material deserving to be studied and developed to emphasize its curative power. Within the framework of the conservation and valorization of the consumable plants cultivated in Algeria, we aimed in the present work to investigate Malva sylvestris cultivated in the region of Sidi Bel Abbes (West of Algeria) as a consumable and a medicinal plant and to evaluate its anti-inflammatory activity.Methods: In this context, an ethnobotanical survey was carried out highlighting the popular knowledge regarding the medicinal uses of this plant. In addition, anti-inflammatory activity was assessed in-vivo using carrageenan-induced paw edema test.Results: Our survey demonstrated that the great mallow is used as a consumable plant and as a treatment against: inflammation, anti-cholesterol and anti-diabetes. For the anti-inflammatory activity, the studied extract proved its effective effect, and was able to inhibit the inflammation induced by carrageenan in a significant way (P≤0.05), after two hours of its administration, and at a dose of 550 mg/Kg PC.Conclusion: Malva sylvestris appears to be an interesting plant that could be used judiciously in the treatment of inflammation.