Autofluorescence and Thoracoscopy

Chrysanthidis, Miltiadis G.

doi:10.1007/978-3-642-38351-9_26

Cited by 2 publications

(2 citation statements)

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“…Autofluorescence for thoracoscopy [Chrysanthidis and Janssen, 2005] To detect and direct biopsies at abnormal sites not visible with conventional white light Sensitivity 100%, specificity 75%…”

Section: Diagnostic Yield 85%mentioning

confidence: 99%

“…Lesions that appear white or pink on white light thoracoscopy become red under green light. Autofluorescence thoracoscopy has high sensitivity 100% but lower specificity 75% [Chrysanthidis and Janssen, 2005]. In another study, oral ingestion of 1.5-2.5 g aminolaevulinic acid (5-ALA) 3-4 hours before thoracoscopy appears to improve detection of malignant mesothelioma not visible on conventional white light thereby facilitating biopsy [Baas et al 2006].…”

Section: Advances In Evaluation Of Pleural Spacementioning

confidence: 99%

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Advances in the diagnosis of pleural disease in lung cancer

See¹,

Lee²

2011

Ther Adv Respir Dis

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Pleural disease in lung cancer can be benign or malignant with the latter carrying a grave prognosis. In this review, we describe and discuss the advances in pleural imaging, procedures, and biomarkers for the diagnosis of pleural diseases in lung cancer. Ultrasound and computed tomography are increasingly applied in the planning of pleural procedures to enhance diagnostic accuracy and safety whilst pleuroscopy gives excellent yield in excess of 93% in the evaluation of cytology negative pleural effusions. Invasion beyond the elastic layer of the visceral pleura upstages lung cancer, and may indicate a need for adjuvant chemotherapy. Biomarkers isolated from pleural fluid or tissue may aid in diagnosis and guide treatment in the future. Magnetic resonance imaging, positron emission tomography, narrow band imaging of the pleura and autofluorescence thoracoscopy are technologies that require further evaluation to better define their respective roles in the diagnostic algorithms of pleural diseases in lung cancer.

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Section: Diagnostic Yield 85%mentioning

confidence: 99%

Section: Advances In Evaluation Of Pleural Spacementioning

confidence: 99%