Autofluorescence spectroscopy in photodynamic therapy for skin rejuvenation: A theranostic approach in aesthetic medicine

Papayan, Garry V.; Podoplekina, Natalya D.; Glagoleva, Ekaterina N.; Petrishchev, Nikolay N.; Galagudza, Michael M.

doi:10.1016/j.pdpdt.2023.103948

Photodiagnosis and Photodynamic Therapy

2024

DOI: 10.1016/j.pdpdt.2023.103948

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Autofluorescence spectroscopy in photodynamic therapy for skin rejuvenation: A theranostic approach in aesthetic medicine

Garry V. Papayan,

Natalya D. Podoplekina,

Ekaterina N. Glagoleva

et al.

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2024

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Cited by 2 publications

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Study on Rice Origin and Quality Identification Based on Fluorescence Spectral Features

Qiu,

Tan,

Zhou

et al. 2024

Agriculture

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The origin of agricultural products significantly influences their quality and safety. Fluorescence spectroscopy was used to analyse Japonica rice 830, grown in different areas of Jilin Province, by examining rice seed, brown rice, and rice flour from 12 origins. Fluorescence spectra were pre-processed through normalisation and smoothing to remove noise. These processed spectra were input into decision trees, support vector machines (SVMs), K-nearest neighbour (KNN), and neural network models for classification. The analysis revealed that the combined four models achieved an average classification accuracy of 98.05% with a computation time of 180 s, while the reduced-scale models improved accuracy to 98.36% and reduced computation time to 11.25 s. Additionally, prediction models using standard rice starch content values across different states achieved R² values over 0.8. This method provides a rapid, precise approach for assessing rice quality and origin, demonstrating significant potential for application in rice analysis.

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Study on Rice Origin and Quality Identification Based on Fluorescence Spectral Features

Qiu,

Tan,

Zhou

et al. 2024

Agriculture

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Molecular Biomarkers in Cutaneous Photodynamic Therapy: A Comprehensive Review

Naharro-Rodriguez,

Bacci,

Fernandez-Guarino

2024

Diagnostics

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Background/Objectives: Photodynamic therapy (PDT) is widely utilized in dermatology for the treatment of various skin conditions. Despite its effectiveness, the exact biomolecular changes underlying therapeutic outcomes remain only partially understood. This review, through a transversal approach, aims to provide an in-depth exploration of molecular biomarkers involved in PDT, evaluate its underlying mechanisms, and examine how these insights can contribute to enhanced treatment protocols and personalized therapy approaches. Methods: A narrative review of the literature was conducted, targeting peer-reviewed articles and clinical trials that focus on PDT and its molecular biomarker effects on dermatological conditions. The databases searched included PubMed, Scopus, and Web of Science, and the inclusion criteria encompassed original research articles, systematic reviews, and meta-analyses in English. Results: PDT effectively reduces the expression of critical biomarkers such as p53, Cyclin D1, and Ki-67 in AK and other cancerous lesions, leading to reduced cell proliferation and increased apoptosis. Additionally, PDT promotes extracellular matrix remodeling and stimulates collagen production, which has a rejuvenating effect on the skin and a promising role in the treatment of chronic wounds. Conclusions: PDT represents a powerful and versatile treatment option for various dermatological conditions due to its ability to target cellular pathways involved in proliferation and apoptosis. Further research into optimizing treatment parameters and combining PDT with other targeted therapies may enhance patient outcomes, reduce resistance, and pave the way for more individualized therapeutic approaches in dermatology.

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Autofluorescence spectroscopy in photodynamic therapy for skin rejuvenation: A theranostic approach in aesthetic medicine

Cited by 2 publications

References 32 publications

Study on Rice Origin and Quality Identification Based on Fluorescence Spectral Features

Study on Rice Origin and Quality Identification Based on Fluorescence Spectral Features

Molecular Biomarkers in Cutaneous Photodynamic Therapy: A Comprehensive Review

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