2016
DOI: 10.21521/mw.5539
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Autogenic platelet-rich plasma: Types, activation methods, and applications

Abstract: SummaryPlatelet-rich plasma (PRP) is an autogenic source of many growth factors that are a part of the healing process and tissue regeneration, which is the cause of its growing popularity in regenerative medicine. In this paper, we present a definition and characteristics of PRP, as well as ways of extracting it. We also present the issue of thrombocyte activation and the impact of thrombocytes on PRP. We explain how to obtain the optimal density of platelets in PRP, as well as its influence on tissues. Addit… Show more

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Cited by 6 publications
(9 citation statements)
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“…Depending on the method of preparation, PRP containing eight times more thrombocytes than in the initial blood can be obtained. Double centrifugation enables one to obtain a higher concentration of thrombocytes and leukocytes in comparison with single centrifugation [28]. We can distinguish platelet-rich plasma containing only thrombocytes, which is referred to as pure PRP (P-PRP), and platelet-rich plasma with the addition of leukocytes (L-PRP) [1].…”
Section: Use Of Platelet-rich Plasma In Personalized Dentistrymentioning
confidence: 99%
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“…Depending on the method of preparation, PRP containing eight times more thrombocytes than in the initial blood can be obtained. Double centrifugation enables one to obtain a higher concentration of thrombocytes and leukocytes in comparison with single centrifugation [28]. We can distinguish platelet-rich plasma containing only thrombocytes, which is referred to as pure PRP (P-PRP), and platelet-rich plasma with the addition of leukocytes (L-PRP) [1].…”
Section: Use Of Platelet-rich Plasma In Personalized Dentistrymentioning
confidence: 99%
“…Periodontitis is the breakdown of periodontal tissues, which occurs along with bone loss and clinical attachment, as well as apical migration of the junctional epithe-lium, which can induce the formation of vertical (angular) and/or horizontal bone defects [25,26]. It manifests in the inflammatory response of periodontal tissues to periodontal pathogens [28,57]. Risk factors for this disease are poor oral hygiene, smoking, genetic predisposition and many systemic diseases, such as diabetes, cardiovascular disease and stroke [25,27].…”
Section: Regenerative Endodontic Treatment (Ret) and Blood Derivativesmentioning
confidence: 99%
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“…Po analizie badań, które zostały przeprowadzone pod względem skuteczności oraz mechanizmu działania PRF, można wywnioskować, że oprócz udziału w odpowiedzi zapalnej oraz tworzeniu rusztowań służy ona skórze także jako zapas czynników wzrostu. Daje to początek procesu angiogenezy, ale także wspomaga gojenie się oraz regenerację tkanek [24][25][26][27][28][29].…”
Section: Fibrynaunclassified