Autogenous bone block in the treatment of teeth with hopeless prognosis

Abstract

Background:Autogenous bone graft, although considered as a gold standard, has been relegated to background because of limited quantity and donor site morbidity. Revival of interest in its use has been reflected by its tremendous capacity for regeneration in less than ideal situation. Bone blocks have been used for implant site augmentation, with varied success.Aim:Aim of the study was to evaluate the efficacy of autogenous bone block in the regeneration of bone, for saving teeth with a hopeless prognosis.Settings and Design:A total of six patients and 12 sites with grade II and III mobile teeth were treated with autogenous bone blocks and fiber splinting.Subjects and Methods:Attachment loss, probing depths, and radiographic bone loss were recorded at baseline and at 12 months interval.Statistical Analysis Used:The Student paired t test was used for evaluation of the changes from baseline to 12 months.Results:At 12 months post-operatively, there was a highly significant amount of bone gain as compared to the baseline. The mean amount of bone loss reduced from 9.41 ± 1.16 to 5.41 ± 1.01. The clinical attachment loss reduced from 7.37 ± 1.24 mm to 3.79 ± 0.89 mm and probing depth reduced from 7 ± 1.67 mm to 5.5 ± 0.63 mm. The grafted bone was observed to have been incorporated with the host bone in most of the sites as evidenced by radiographs.Conclusions:For teeth with hopeless prognosis, this method can be considered to be a very viable alternative to extraction and replacement by costly implants.

The Paracrine Role of Endothelial Cells in Bone Formation via CXCR4/SDF-1 Pathway

“…However, this technique is associated with many limitations, such as insufficient available bone at the donor site and lack of vascularity. Thus bone blocks can lead to significant volumetric reduction, and most of the cells in the block do not survive [6]. Other strategies have been developed as alternatives to autologous bone block, including those relying on the osteoconductive or osteoinductive capabilities of an implanted tissue (such as allograft or demineralized bone matrix) or synthetic material (such as bio ceramics in different forms and compositions) [7,8].…”

Use of Injectable Platelet-Rich Fibrin Accompanied by Bone Graft in Socket Endurance: A Radiographic and Histological Study

“…The utilization of the combination allograft stemmed in a statistically suggestive escalation in the average amount of viable bone development and a decrease in the remaining amount of non-viable material. Harvesting autogenous bone grafts poses substantial challenges [ 86 - 88 ] and necessitates a second surgical site [ 89 , 90 ]. At 18-20 weeks after succeeding alveolar ridge perpetuation, the utilization of a combination allograft yielded a significantly greater average formation of vivacious osseous matter and reduced the number of transplanted substances [ 91 - 93 ].…”

“…Harvesting autogenous bone grafts poses substantial challenges [86][87][88] and necessitates a second surgical site [89,90]. At 18-20 weeks after succeeding alveolar ridge perpetuation, the utilization of a combination allograft yielded a significantly greater average formation of vivacious osseous matter and reduced the number of transplanted substances [91][92][93].…”

Evaluation of Simvastatin Efficacy on Bone Regeneration for Socket Preservation

“…The gold standard still considered for grafting procedures is autogenous bone but is associated with several problems including morbidity of the donor site and limitation of the amount of bone that can be harvested (6,7) . Until now, there is still no consensus concerning which material or technique is the most effective not only in limiting post extraction resorption but also at the same time in assisting the regeneration of high-quality bone (8) .…”