Autogenous dentin combined with mesenchymal stromal cells as an alternative alveolar bone graft: an in vivo study

Barreiro, Bernardo Ottoni Braga; Koth, Valesca Sander; Sesterheim, Patrícia; Salum, Fernanda Gonçalves; Rübensam, Gabriel; Augustin, Adolpho Herbert; Cherubini, Karen

doi:10.1007/s00784-022-04840-z

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2024

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Cited by 2 publications

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“…13 Furthermore, they exhibit similar physicochemical properties. 14,15 These similarities make dentin wellsuited for the regeneration of missing hard tissue. DDM contains a significant amount of inorganic hydroxyapatite (HA), a vital component for the process of osteogenesis.…”

Section: Introductionmentioning

confidence: 99%

A novel bi-layered asymmetric membrane incorporating demineralized dentin matrix accelerates tissue healing and bone regeneration in a rat skull defect model

Li,

Luo,

Yang

et al. 2024

Biomater. Sci.

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Section: Introductionmentioning

confidence: 99%

A novel bi-layered asymmetric membrane incorporating demineralized dentin matrix accelerates tissue healing and bone regeneration in a rat skull defect model

Li,

Luo,

Yang

et al. 2024

Biomater. Sci.

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Advances in autogenous dentin matrix graft as a promising biomaterial for guided bone regeneration in maxillofacial region: A review

Sun,

Yin,

Yang

et al. 2024

Medicine

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Autogenous dentin matrix (ADM), derived from a patient’s extracted tooth, can be repurposed as an autologous grafting material in reconstructive dentistry. Extracted teeth provide a source for ADM, which distinguishes itself with its low rejection rate, osteoinductive capabilities and ease of preparation. Consequently, it presents a viable alternative to autogenous bone. Animal studies have substantiated its effective osteoinductive properties, while its clinical applications encompass post-extraction site preservation, maxillary sinus floor augmentation, and guided bone tissue regeneration. Nevertheless, the long-term efficacy of ADM applied in bone regeneration remains underexplored and there is a lack of standardization in the preparation processes. This paper comprehensively explores the composition, mechanisms underlying osteoinductivity, preparation methods, and clinical applications of ADM with the aim of establishing a fundamental reference for future studies on this subject.

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Autogenous dentin combined with mesenchymal stromal cells as an alternative alveolar bone graft: an in vivo study

Cited by 2 publications

References 43 publications

A novel bi-layered asymmetric membrane incorporating demineralized dentin matrix accelerates tissue healing and bone regeneration in a rat skull defect model

A novel bi-layered asymmetric membrane incorporating demineralized dentin matrix accelerates tissue healing and bone regeneration in a rat skull defect model

Advances in autogenous dentin matrix graft as a promising biomaterial for guided bone regeneration in maxillofacial region: A review

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