Autoimmune Encephalitis and Paraneoplastic Neurologic Syndromes

Abstract

Background and ObjectivesAutoimmune encephalitis (AIE) and paraneoplastic neurologic syndromes (PNSs) encompass a heterogeneous group of antibody-associated disorders. Both the number of syndromes and commercially available antibody tests have increased considerably over the past decade. Highquality population-based data on epidemiology of these disorders and real-world performance of antibody tests are needed. MethodsIn this nationwide retrospective cohort study, we identified all serum and CSF samples tested for antibodies against intracellular antigens