Autoimmune haemolytic anaemia associated with transitional cell carcinoma

Hibino, Seikei; Stoller, RonaldG.; Jacobs, SamuelA.

doi:10.1016/0140-6736(92)91449-i

Cited by 7 publications

(4 citation statements)

References 5 publications

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“…In patients with recurrent cancer associated with AIHA, AIHA responded well to chemotherapy [48,49], in one case of a recurrent bladder cancer to resection and chemotherapy [51] and in one renal cancer to nephrectomy [52]. Th ere were two patients who had AIHA after treatment without recurrence.…”

Section: Discussionmentioning

confidence: 99%

“…In 7 patients AIHA did not occur at the time of the initial diagnosis of the cancer, but it occurred when the tumor had relapsed [26,[48][49][50][51][52][53]. Th ese patients had breast cancer (n = 2), lung cancer (n = 1) and there was one case of renal cell, bladder, ovarian and cervix cancer, each.…”

Section: Aiha In Patients With Recurrent Solid Cancers (Table 3)mentioning

confidence: 99%

“…Th e complete remissions were sustained over several months in both cases. In addition, one patient achieved a complete remission after the resection and chemotherapy of a recurrent transitional bladder carcinoma [51] and two other patients (recurrent renal cell and ovarian cancer) had a remission of AIHA after steroids [52,53].…”

Section: Aiha In Patients With Recurrent Solid Cancers (Table 3)mentioning

confidence: 99%

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Autoimmune hemolytic anemia as a paraneoplastic phenomenon in solid tumors: A critical analysis of 52 cases reported in the literature

Puthenparambil

Lechner

Kornek

2010

Wien Klin Wochenschr

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Autoimmune hemolytic anemia (AIHA) is a well known paraneoplastic phenomenon in lymphoproliferative disorders but there are also a number of case reports of such an association with solid tumors. We have analysed 52 cases of this association reported in the literature. We found that AIHA may occur prior to, concurrent with cancer or well after end of treatment, either as a sign of recurrence or in complete remission of the cancer. 70% of the patients had warm antibody and 30% cold antibody AIHA. Some patients had additional antibodies such as platelet antibodies (Evans syndrome), lupus anticoagulants or antibodies to C1 esterase inhibitor. AIHA occurred in almost all types of cancers, but it was relatively more common in renal cell cancer and Kaposi sarcoma compared to other cancers. In early stage cancers, in particular in renal cell cancers, curative resection of the cancers led to complete, often sustained remission of AIHA within a short time in a number of patients. Resection of the tumor had also beneficial effects in some metastatic cancers. Patients who had a response to resection of the tumor were often refractory to steroid treatment before surgery, while some responses to steroids were observed in patients with metastatic cancer. The study of cancer patients with autoimmune diseases may provide important insights into the biology of tumors.

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Section: Discussionmentioning

confidence: 99%

Section: Aiha In Patients With Recurrent Solid Cancers (Table 3)mentioning

confidence: 99%

Section: Aiha In Patients With Recurrent Solid Cancers (Table 3)mentioning

confidence: 99%

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Autoimmune hemolytic anemia as a paraneoplastic phenomenon in solid tumors: A critical analysis of 52 cases reported in the literature

Puthenparambil

Lechner

Kornek

2010

Wien Klin Wochenschr

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“…There is accumulating evidence that suggests that the neoplastic cells of at least some patients with these hematologic malignancies can produce RBC-specific autoantibodies (6,11). AIHA also occurs in patients with various non-hematologic tumors, including breast, lung, digestive tract, and prostate carcinomas; hypernephroma; and seminoma (7,(12)(13)(14)(15)(16)(17). However, the etiology of AIHA associated with non-hematologic malignancies still remains poorly understood (14,15).…”

Section: Discussionmentioning

confidence: 99%

Pleural Solitary Fibrous Tumor Complicated with Autoimmune Hemolytic Anemia

et al. 2014

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We herein report a 74-year-old woman who presented with autoimmune hemolytic anemia (AIHA) associated with pleural solitary fibrous tumor (SFT). Her AIHA was initially treated with 1 mg/kg daily of oral prednisolone (PSL) for 2 months, which had a limited effect. However, after surgical tumor resection, the patient showed remarkable improvement of AIHA with normalizations of serum lactate dehydrogenase and bilirubin levels, and we were able to rapidly reduce the PSL dosage. This is the first description of a case of AIHA caused by SFT.

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Classification and Clinical Characteristics of Autoimmune Hemolytic Anemias

Petz

2004

Immune Hemolytic Anemias

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Autoimmune haemolytic anaemia associated with transitional cell carcinoma

Cited by 7 publications

References 5 publications

Autoimmune hemolytic anemia as a paraneoplastic phenomenon in solid tumors: A critical analysis of 52 cases reported in the literature

Autoimmune hemolytic anemia as a paraneoplastic phenomenon in solid tumors: A critical analysis of 52 cases reported in the literature

Pleural Solitary Fibrous Tumor Complicated with Autoimmune Hemolytic Anemia

Classification and Clinical Characteristics of Autoimmune Hemolytic Anemias

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